Salbutamol CPG

Question 1

Salbutamol - Presentation

Answer 1

5 mg in 2.5 mL polyp

pMDI (100 mcg per actuation)

Question 2

Salbutamol - Pharmacology

Answer 2

A synthetic beta adrenergic stimulant with primary beta 2 effects

Action:

• Causes bronchodilatation

Question 3

Salbutamol - Metabolism

Answer 3

By the liver; excreted by the kidneys

Question 4

Salbutamol - Primary emergency indications

Answer 4

1. Respiratory distress with suspected bronchospasm:
   - asthma
   - severe allergic reactions
   - COPD
   - smoke inhalation
   - oleoresin capsicum spray exposure

Question 5

Salbutamol - Contraindications

Answer 5

1. None of significance in the above indications

Question 6

Salbutamol - Precautions

Answer 6

1. Large doses of Salbutamol have been reported to cause intracellular metabolic acidosis

Question 7

Salbutamol - Route of administration

Answer 7

Nebulised

pMDI

Question 8

Salbutamol - Side effects

Answer 8

Sinus tachycardia

Muscle tremor (common)

Question 9

Salbutamol - Special notes

Answer 9

Salbutamol nebules / polyps have a shelf life of one month after the wrapping is opened. The date of the opening of the packaging should be recorded and the drug should be stored in an environment of < 30°C

Although infrequently used, Salbutamol by IV infusion may be required during inter hospital transfers of some women in premature labour

The dose is to be prescribed and signed by the referring hospital medical officer

Nebulised effects:

Onset: 5 - 15min

Peak: n/a

Duration: 15 - 50min