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Naplex > Rx Files Men's Health > Flashcards

Rx Files Men's Health Flashcards

1
Q

Define ED

A

inability to achieve or sustain an erection

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2
Q

What is on the differential diagnosis as to the cause of ED?

A
  • cardiovascular disease
  • diabetes
  • ethanol/ substance abuse
  • psychological factors
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3
Q

What drugs may cause ED?

A
  • antipsychotics
  • antidepressants
  • propranolol
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4
Q

Sildenafil brand

A

Viagra

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5
Q

Sildenafil mechanism of action

A

selective PDE-5 inhibitor

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6
Q

Sildenafil dosing

A 
50 mg (25 mg for elderly) one hour prior to intercourse. 
Max dose 100 mg/day
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7
Q

Sildenafil ADRs

A
  • headache
  • flushing
  • priapism
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8
Q

What may happen with high sildenafil levels?

A

PDE-6 may be affected which plays a role in photo-transduction in the retina - patient may complain of blue-tinted vision

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9
Q

What is a serious drug interaction with sildenafil?

A

Nitrates can cause fatal hypotension

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10
Q

What is the difference between sildenafil and newer analogues?

A

greater selectivity for PDE-5 with longer half life

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Naplex (8 decks)

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