Rx Files CCBs Flashcards

1
Q

Primary uses of CCBs

A

angina
select arrhythmias
HTN

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2
Q

What are the types of Ca channels?

A

L, T, N, P

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3
Q

How are CCBs eliminated?

A

hepatically metabolized

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4
Q

nifedipine brand

A

Adalat
Adalat CC
Procardia
Procardia XL

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5
Q

Nifedipine chemical class

A

dihydropyridines

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6
Q

Nifedipine adverse effects

A
  • flushing/ rash
  • peripheral edema
  • dizziness
  • gingival hyperplasia
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7
Q

Nifedipine onset of action

A

PO 20 minutes

SL 1-5 minutes

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8
Q

Nifedipine dosage

A

IR: 10 mg PO TID
SR: 30 - 90 mg PO daily

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9
Q

Adalat CC should be taken on (full/empty) stomach.

A

empty

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10
Q

Counselling point on nifedipine SR formulations

A

SR tablet cores may appear in stool

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11
Q

Diltiazem brand

A
Cardizem CD
Cardizem
Dilacor
Dilacor XR
Tiamate
Tiazac
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12
Q

Diltiazem prolongs (AV/SA) conduction.

A

AV

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13
Q

Diltiazem chemical class

A

benzothiazepine

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14
Q

Diltiazem dosage forms

A

IV

PO

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15
Q

What is diltiazem IV most commonly used to treat?

A

atrial fibrilation

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16
Q

Diltiazem adverse effects

A
  • bradycardia
  • AV block
  • peripheral edema
  • flushing
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17
Q

Diltiazem IV dosage

A

bolus: 0.25 mg/kg over 2 minutes
infusion: 10 mg/hr

18
Q

Diltiazem IV to PO

A

Use IR PO dosage form and overlap by about 3 hours

19
Q

Why should diltiazem be used cautiously in CHF?

A

strong negative inotrope

20
Q

Verapamil brand

A
Calan
Calan SR
Covera HS
Isoptin
Isoptin SR
Verelan
21
Q

Verapamil chemical class

A

phenylalkylamine

22
Q

Verapamil prolongs (AV/SA) node conduction

A

AV

23
Q

Verapamil should be used cautiously in patients with (tachy/brady)cardia.

A

bradycardia

24
Q

Verapamil adverse reactions

A
  • hypotension
  • CHF
  • peripheral edema
  • constipation
25
Q

(T/F) Verapamil is available as IV.

A

True

26
Q

Verapamil dosage

A

IR: 80 - 120 mg PO TID

27
Q

Amlodipine brand

A

Norvasc

28
Q

Amlodipine chemical class

A

dihydropyridine

29
Q

Amlodipine adverse effects

A
  • peripheral edema

- flushing

30
Q

What is the favorable characteristic of amlodipine?

A

daily dosing

31
Q

Amlodipine dosage

A

5-10 mg PO QD

32
Q

Amlodipine is particularly selective for (myocardium/vasculature).

A

vasculature

33
Q

Nimodipine brand

A

Nimotop

34
Q

Bepridil

A

Vascor

35
Q

Felodipine

A

Plendil

36
Q

Nicardipine

A

Cardene

37
Q

Nisoldipine

A

Sular

38
Q

Nitrendipine

A

Cardif

Nitrepin

39
Q

Lacidipine

A

Motens

40
Q

Lercanidipine

A

Zanidip