RVT-Respiratory Drugs Flashcards
Which bronchodilators act to stabilize mast cells and are a mucolytic?
B2 adrenergic agonists-
Terbutaline
Albuterol
What are the anticholinergic bronchodilators?
Atropine
Aminopentamide
Glycopyrrolate
What is the danger of owners using over the counter decongestants for their pets?
If the pet has any underlying cardiac issues, these drugs can be dangerous due to Beta1 sympathetic receptor stimulation.
How do bronchodilators work?
They expand bronchi smooth muscle to allow for easier air passage
Which respiratory drugs have a narrow therapeutic range?
Methylxanthines-
Aminophylline
Theophylline
Theobromine
What are the side effects of antihistamines?
CNS depression
Dry mouth
Urine retention
What 3 drugs are B2 adrenergic agonists?
Terbutaline
Albuterol
Epinephrine
( Think B=Bute)
What are the causes of bronchoconstriction?
Histamine release binding with receptors at the smooth muscle in lungs causing inflammation
Dilation inhibition caused by other drugs blocking B2 adrenergic receptors
Parasympathetic ach binding increasing resp secretions
What are the side effects of anticholinergic bronchodilators?
Tachycardia
Dry mouth
Dry eyes
How do decongestants work?
They stimulate the SNS alpha1 receptors causing reduced swelling in sinuses.
Which bronchodilator is for life threatening emergencies?
Epinephrine
What are the side effects of the methylxanthines?
CNS excitement
Tremors
Ataxia
Which drug is used as a CNS stimulant to stimulate breathing?
Doxapram
Why should we be careful using decongestants in animals with cardiac concerns?
Some decongestants can affect Beta1 receptors as well as the Alpha1 receptors
What 2 drugs are decongestants?
Phenylephrine
Pseudonephrine
How do anticholinergic bronchodilators work?
They bind to ach receptors to prevent bronchoconstriction.
- they block the PSNS nerve reflexes that cause the airways to constrict= they remain open
How do the B2 adrenergic agonist bronchodilators work?
Stimulate the B2 receptors
-relaxes bronchiole smooth muscle causing them to dilate
What modes of administration ate terbutaline and AlbuterolW available in?
Tablets and inhalers
What drugs are in the methylxanthine class?
Theobromine
Aminophylline
Theophylline
Which drugs would be used for allergic reactions that affect the lungs?
Antihistamines-
Diphenhydramine
Chlorphenarimine
Which reversal agent works only for a short time and may need additional dosing?
Naloxone