RVT-Respiratory Drugs Flashcards

1
Q

Which bronchodilators act to stabilize mast cells and are a mucolytic?

A

B2 adrenergic agonists-
Terbutaline
Albuterol

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2
Q

What are the anticholinergic bronchodilators?

A

Atropine
Aminopentamide
Glycopyrrolate

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3
Q

What is the danger of owners using over the counter decongestants for their pets?

A

If the pet has any underlying cardiac issues, these drugs can be dangerous due to Beta1 sympathetic receptor stimulation.

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4
Q

How do bronchodilators work?

A

They expand bronchi smooth muscle to allow for easier air passage

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5
Q

Which respiratory drugs have a narrow therapeutic range?

A

Methylxanthines-
Aminophylline
Theophylline
Theobromine

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6
Q

What are the side effects of antihistamines?

A

CNS depression
Dry mouth
Urine retention

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7
Q

What 3 drugs are B2 adrenergic agonists?

A

Terbutaline
Albuterol
Epinephrine
( Think B=Bute)

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8
Q

What are the causes of bronchoconstriction?

A

Histamine release binding with receptors at the smooth muscle in lungs causing inflammation
Dilation inhibition caused by other drugs blocking B2 adrenergic receptors
Parasympathetic ach binding increasing resp secretions

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9
Q

What are the side effects of anticholinergic bronchodilators?

A

Tachycardia
Dry mouth
Dry eyes

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10
Q

How do decongestants work?

A

They stimulate the SNS alpha1 receptors causing reduced swelling in sinuses.

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11
Q

Which bronchodilator is for life threatening emergencies?

A

Epinephrine

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12
Q

What are the side effects of the methylxanthines?

A

CNS excitement
Tremors
Ataxia

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13
Q

Which drug is used as a CNS stimulant to stimulate breathing?

A

Doxapram

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14
Q

Why should we be careful using decongestants in animals with cardiac concerns?

A

Some decongestants can affect Beta1 receptors as well as the Alpha1 receptors

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15
Q

What 2 drugs are decongestants?

A

Phenylephrine

Pseudonephrine

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16
Q

How do anticholinergic bronchodilators work?

A

They bind to ach receptors to prevent bronchoconstriction.

- they block the PSNS nerve reflexes that cause the airways to constrict= they remain open

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17
Q

How do the B2 adrenergic agonist bronchodilators work?

A

Stimulate the B2 receptors

-relaxes bronchiole smooth muscle causing them to dilate

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18
Q

What modes of administration ate terbutaline and AlbuterolW available in?

A

Tablets and inhalers

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19
Q

What drugs are in the methylxanthine class?

A

Theobromine
Aminophylline
Theophylline

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20
Q

Which drugs would be used for allergic reactions that affect the lungs?

A

Antihistamines-
Diphenhydramine
Chlorphenarimine

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21
Q

Which reversal agent works only for a short time and may need additional dosing?

A

Naloxone

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22
Q

Which respiratory stimulant is used to reverse xylazine?

A

Yohimbine

23
Q

What are the side effects of Yohimbine?

A

CNS stimulation

Muscle tremors

24
Q

What are the two ways to suppress a non-productive cough?

A

Centrally acting

Local

25
Q

In cases of tracheitis or tracheobronchitis, which class of drugs may be used?

A

Antitussives

26
Q

What are the two types ( subheadings) of Antitussives available?

A

Controlled

Non-controlled

27
Q

What side effects does atropine have?

A
Dry mouth
Dry Eyes
Tachycardia
Vomiting
Constipation
Urinary retention
28
Q

What are the two classes of bronchodilators?

A

Anticholinergics

B2 Adrenergic agonists

29
Q

What are some alternate methods we can suggest for treatment of pets with congestion?

A

Cool air vaporizers
Warm compresses
Saline solution drops

30
Q

Besides being an expectorant, what is guafenesin used for?

A

Muscle relaxant in horses

31
Q

Which drug is used for emergency treatment for feline asthma?

A

Terbutaline

32
Q

Which class of respiratory drugs work by inhibiting an enzyme that promotes bronchoconstriction?

A

Methylxanthines

33
Q

How do antihistamines work?

A

Histamines are released from mast cells- they bind to receptors on smooth muscle causing bronchoconstriction = Antihistamines block the smooth muscle receptors

34
Q

Which respiratory stimulant is used as a reversal agent for opioids?

A

Naloxone

35
Q

Which Antitussive drugs are controlled?

A

Morphine
Codeine
Hydrocodone
Butorphanol

36
Q

Which of the controlled Antitussives is the most powerful?

A

Hydrocodone

37
Q

Which of the controlled Antitussive drugs has the least cardiovascular and respiratory depressive affects?

A

Butorphanol

38
Q

Which Antitussive drug is a combination of antihistamine and prednisolone?

A

Trimeprazine ( Vanectyl-P)

39
Q

What are the side effects of trimeprazine?

A
PU/PD
Polyphagia
Sedation
Depression
Hypotension
40
Q

Which Antitussive drug is not often used in veterinary medicine but is significant as owners may give it at home?

A

Dextramethoprhan

41
Q

Which of the Antitussives are opioids?

A

Codeine
Morphine
Hydrocodone
Butorphanol

42
Q

Which reversal drug can be used for the opioid class of Antitussives?

A

Naloxone

43
Q

What are the common opioid side effects?

A

Sedation and constipation

44
Q

Which class of drugs will be used to remove mucus that cannot easily be removed by cilia?

A

Mucolytics and expectorants

45
Q

How do mucolytics work?

A

Break down the mucus by breaking disulphide bonds….allows mucus to be moved out of resp tract easier

46
Q

Which drug is a mucolytic?

A

Acetylcysteine

47
Q

How can acetylcysteine be administered?

A

PO
IV
Nebulizer

48
Q

Besides being a mucolytic, what else can acetylcysteine be used for in cats?

A

Used to treat acetaminophen toxicity in cats

49
Q

Which medication could be used on a productive cough?

A

Guafenesin - makes the mucus easier to cough out

50
Q

What kind of drug is guafenesin?

A

Expectorant

51
Q

Which medication is used to keep dry, irritated tissues moist?

A

Guafenesin

52
Q

Does the use of an expectorant increase or decrease muco content?

A

Increases - waters it down so easier to bring up

53
Q

Which drugs are used to treat feline asthma?

A
Diphenhydramine/Chlorphenarimine
Aminophyline
Terbuterol
Albuteral
(Remember DATA)