RTA types

Question 1

type I RTA characteristics

Answer 1

increased acidity of the plasma due to failure to secrete acid. problem acidifying usually in the ducts of the distal nephron. leads to academia and hypokalemia

Question 2

typical presentation of RTA 1

Answer 2

normal anion gap metabolic acidosis. hypokalemia, hypocalcemia, hyperchloremia, urinary stones, nephrocalcinosis bone demineralization, sjogrens syndrome.

Question 3

type II characteristics

Answer 3

proximal RTA. failure of the proximal tubular cells to reabsorb filtered bicarb form the urine. leading to bicarb wasting. fanconi syndrome

Question 4

what does RTA II present as

Answer 4

phosphaturia, glycosuria, aminoaciduria, uricosuria, and tubular proteinuria

Question 5

type IV RTA

Answer 5

this is not a tubular disorder. it is a mild metabolic acidosis due to physiological reduction in proximal tubular ammonium excretion secondary to hypoaldosteronism resulting in decreased buffering capacity.

Question 6

what is the cardinal feature of type IV RTA

Answer 6

hyperkalemia.