Rotation Gouge Flashcards
Sebulex
An OTC medicated shampoo for dandruff
Carmol HC
A topical combination moisturizer that uses urea and hydrocortisone
Lamasil
Terbenafine
What is the MOA of terbenafine
Inhibits squalene epoxidase and therefore reduces fungal cell membrane ergosterol synthesis
What is the indication for terbenafine
Antifungal for onychomychosis
What is the mechanism of Naftin
Topical antibiotic that inhibits the fungal squalene epoxidase reducing fungal cell membrane ergosterol synthesis
Dovinex
Calcipotriene
What is the MOA of calcipotriene
Used for the treatment of psoriasis
Exact mechanism is unknown; binds to vitamin D receptors inducing cell differentiation and inhibiting cell proliferation
Clobex
Clobetasol topical
What are the indications for clobex
Psoriasis and dermatoses that are steroid responsive
Olux
Clobetasol topical
Nizoral
Ketoconazole
What are the indications for ketoconazole
Tinea versicolor
Seborheric dermatitis
tinea capitis adjunct
What are Dennie Morgan folds
A fold or line in the skin below the lower eyelid caused by edema in atopic dermatitis
A diagnostic marker for allergy
What birth control pills can be used for a means of treating acne
Yaz and Yasmin
Drosperinone component is potassium sparing antiadrenergic (suppresses FSH & LH)
What additional labs need to be ordered for patients starting yaz or Yasmin?
Electrolytes for potassium at drug initiation and again at 30 days
Duac
Clinicamycin and benzoyl peroxide
Indicated for acne
Retin- A micro
Tretinoin topical
Indicated for acne vulgaris
What is the mechanism for topical retinoids
Binds to retinoic acid receptors, stimulating epethelial cell turnover
What is the shorthand “UD” stand for?
As directed
What is the most common etiology for acne In A jawline distribution
Hormonal
Discuss demadex folicularum and d. Brevis
A species of the face mite
Usually found in greater numbers around the cheeks, nose, eye brows, eye lashes and forehead
D. Brevis is shorter and has a pointier tale when compared to folicularum.
Pityriasis alba
Common in pediatrics and is a loss of melanocyte density
Tinea versicolor
Discoloration of the skin due to (malassezia furfur) pityrosporum ovaleand p. biculare
Vitiligo
Autoimmune response that causes hypo pigmentation
Two types a and b
A- symmetrical
B- asymmetrical
Desonate
Desonide topical (class VI steroid)
Nevus hypo pigmentation
Nevus with inadequate or dysfunctional melanocytes
Ephilides
Freckle
Lentigo
Liver spots (sun spots)
Increases in number and prevalence with age
Skin tag
Acrochordon
Stucco keratosis
Referred to as barnacles
Common, nearly inconspicuous papular warty lesions occurring in the lower legs especially around the Achilles’ tendon.
Prurigo nodularis
Uncommon disease
Nodular form of lichen simplex
Intractable pruritis
Nodules are typically 1-2 cm
Generalize the Fitzpatrick skin scale
Type I blue eyed celts with high susceptibility for skin cancer
Type VI African American with low susceptibility for skin cancer
Mucosis fungiodes
Most common type of cutaneous T cell lymphoma
Typical affects skin but May progress internally
Onychodystrophy
Nail pitting and onycholysis
Nail pitting associated with psoriasis is most commonly associated with what additional characteristic
Psoriatic arthritis: 90% of patients with psoriatic arthritis have nail changes
Trachyonychia
Psoriatic nails that appear as if they have been scraped with sand paper
What nail features are associated with psoriasis
Nail pitting
Trachyonchia
Onycholysis
Subungal hyperkeratosis
What are the treatment options for systemic psoriasis
- Phototherapy: nbUVB or PUVA
- Oral meds: Methotrexate, acetretin, cyclosporine
- Biologics: alefacept, TNF-a inhibitors
Alefacept
Immune modulator that works by inhibiting T cells
What are the types of psoriasis?
Based on their morphology
- Plaque
- Gutate
- Inverse
- Pustular
- Erythrodermic
What are the types of rosacea
- Erythematotelangectetic
- Papulopustule (no comedones)
- Phymatous
Why should you not use strong steroids on the face
Induce steroid rosacea: eruption of papular around the mouth.
If a pt has a perioral dermatitis that looks like rosacea, ask about topical steroid use.
What are the diagnostic criteria for lupus
Mnemonic DOPAMINE RASH
D: discoid lupus O: oral ulcers P: photosensitivity A: arthritis M: malar rash I: immunologic criteria (ANA) N: neurological changes E: increased ESR
R: renal disease
A: ANA +
S: serositis
H: hematologic disease
What is the primary symptom of atopic dermatitis
Itch
It’s the itch that rashes
What are the side effects of oral isoretinoin
Birth defects Dry eyes Dry lips Nose bleeds Hypertriglyceridemia Myalgias and elevated CK
What are the types of melanoma
Superficial spreading Nodular Lentigo maligna Acral lentiginous Amelanotic
Actinic purpura
Senile bruising
Actinic cheilitis
AK’s on the lips
What will the histopathology show for muluscum contagiosum
Henderson Patterson bodies
What medications are fungistatic
Imidazoles
What medications are fungicidal
Allylamines, benzylamines
Terbenafine
Butenafine
Cyclopirox
What is the topical treatment for candida infections
Nystatin ointment
What is the most common dermatological complaint of school aged children?
Tinea capitis
Caused by trichophyton tonsurans
What are the two types of contact dermatitis
Irritant contact dermatitis (ICD)
Allergic contact dermatitis (ACD)
What is erysipelas
Superficial cellulitis with marked dermal lymphatic involvement
What is the hallmark lesion of leukocytoclastic vasculitis (small vessel vasculitis)
Palpable purpura
What is asteototic dermatitis
Xerotic eczema
More common in the elderly during the winter with multiple hot showers.
Pruritis is resolved with prolonged baths, but returns shortly after
What is lipodermatosclerosis
Subcutaneous fat is replaced by fibrosis that eventually impedes venous and lymphatic flow leading to edema above the fibrosis
What topical therapies can be used to inhibit keratinocytes proliferation
Tar
Vitamin D analog
Tazarotene
What is a furuncle
Boil
An acute, round, tender, circumscribed, perifollicular abscess that generally ends in central suppurations
What is a carbuncle
A coalescence of several inflamed follicles into a single inflammatory mass with purulent drainage from multiple follicles
What is echthyma
An ulcerative form of impetigo in which the lesions extend through the epidermis and deep into the dermis
Consist of punched out ulcers
What is necrotizing fasciitis
Life treating infection of the fascia just above the muscle layer. Rapidly expanding dusky, edematous red plaque with blue discoloration.
Anesthesia of the skin is the characteristic finding
What is cellulitis
Bacterial infection of the dermis
Cimex lectularius
Bed bugs
What leads to tissue destruction with a brown recluse spider bite
Sphingomyelenase D
Compound W
An over the counter wart removing agent that has an active ingredient of salicylic acid
What medications are associated with SJS/TEN
SATAN
Sulfa antibiotics Allopurinol Tetracyclines Anticonvulsants NSAIDs
What is a sclerosing agent that can be used for spider angiomas
glycerine
What is the treatment for keloids
- inject smaller keloids on the face with 2.5 mg/ml kenolog
- inject keoloids on the scalp with 10 mg/ml kenolog.
- inject large keloids with 20-40 mg/ml kenolog
Elidel
pimecrolimus
What is the indication for elidel
atopic dermatitis
What is the mechanism for elidel
inhibits T lymphocyte activation
What is paronychia
a nail disease that is often a tender fungal or bacterial infection of the hand or foot where the nail and the skin meet at the side or base of a finger or toe nail
What are the classification levels of retinoids
From Strongest to Weakest
- isotretinoin
- tazorotene
- tretinioin
- adapalene
- retinaldehyde
- retinol
- retinyl palmitate
What are the classification levels of topical steroids
I - Clobetasol 0.05% II - Fluocinonide 0.05% III- Triamcinolone ointment 0.1% IV - Triamcinolone cream 0.1% V - Triamcinolone lotion 0.1% VI - Fluocinolone acetonide 0.01% VII - desonide 0.05% VII - Hydrocortisone 1 %
Retin-A
tretinoin