Role Of Coenzymes Flashcards
1
Q
What is Coenzyme A?
A
- Non organic molecule
- Nucleoside and a vitamin
- In link reaction, CoA binds to remainder of pyruvate molecule forming Acetyl CoA
- Supplies acetyl group to Kreb’s cycle (for respiration)
2
Q
What do NAD and FAD do? (generally)
A
- Accept hydrogens (become reduced)
- H atoms transferred from different stages of respiration to electron transport chain
- H atoms (H+ ions and electrons) removed, so coenzymes are oxidised
3
Q
What is the role of NAD and FAD in the synthesis of ATP?
A
- NADH and FADH2 donate electrons to electron transport chain and release H+ ions
- Electron transport chain releases energy via oxidation and reduction reactions, so H+ diffuses by active transport from inner mitochondrial membrane to intermembrane space
- H+ gradient created
- Movement of H+ down gradient by facilitated diffusion through ATP synthase gives energy required for ATP synthesis
4
Q
Which stages of respiration do reduced NAD and FAD come from?
A
NADH :
- 2 from glycolysis
- 2 from link reaction
- 6 from Kreb’s cycle
FADH2 :
- 2 from Kreb’s cycle