Oxidative Phosphorylation Flashcards

1
Q

Where does it occur?

A

Inner Mitochondrial Membrane

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2
Q

What happens in Oxidative Phosphorylation?

A
  • Hydrogen atoms from NADH and FADH2 released
  • H atoms split to H+ ions and electrons
  • Electrons enter electron transport chain
  • Energy released used to transport H+ ions across inner mitochondrial membrane from matrix to intermembrane space
  • Concentration of protons between these 2 cause protons to diffuse by facilitated diffusion through channel protein ATP Synthase
  • As H+ diffuses through ATP Synthase, conformational change in its shape occurs allowing ADP and Pi to combine forming ATP
  • Movement of protons down concentration gradient provides energy for ATP synthesis
  • Oxygen is the final electron acceptor and combines with protons and electrons at the end of the electron transport chain to form water.
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3
Q

What is the chemiosmotic theory? (short)

A
  • Energy from electrons passed through electron transport chain is used to pump H+ ions against concentration gradient from mitochondrial matrix to intermembrane space
  • H+ ions then diffuse via facilitated diffusion through ATP Synthase transport proteins back into the matrix
  • Energy of H+ ions flowing down concentration gradient results in phosphorylation of ADP into ATP by ATP Synthase
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