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MSII Unit II > Rock & Roll > Flashcards

Rock & Roll Flashcards

1
Q

Autoimmune diseases such as SLE can cause?

A

Monocytosis

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2
Q

Eosinophilia is >__% of eosinophil?

A

> 7%

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3
Q

Toxic granulation and Dohle bodies in neutrophil indicate?

A

Bacterial sepsis

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4
Q

Lymphocytes with abundant cytoplasma can be from?

A

IM

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5
Q

CD68 is a ___ marker?

A

Macrophages

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6
Q

Lymphoma can be associated with ___?

A

Wiskott-Aldrich syndrome

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7
Q

What is t(8;14) translocation?

A

Burkitt lymphoma

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8
Q

t(14;18)?

A

Follicular lymphoma

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9
Q

t(11;14)?

A

Mantle lymphoma

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10
Q

Only one light chain is expressed in ___?

A

B cell neoplasia

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11
Q

Small lymphocytic lymphoma is associated with?

A

CLL

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12
Q

Involvement of Waldeye ring is commonly associated with?

A

NHL and Diffuse large B cell lymphoma

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13
Q

Can diffuse large B cell lymphoma be cured?

A

Yes

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14
Q

BCL6 gene rearrangement is associated with?

A

Diffuse large B cell lymphoma

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15
Q

Heinz bodies are associated with?

A

G6PD deficiency

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16
Q

t(15;17)?

A

APL, one kind of AML—->cause DIC

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17
Q

Features of myelodysplasia?

A

Can be caused by chemo therapy—>abnormal cell maturation in the marrow—>pancytopenia

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18
Q

PCV can lead to?

A

Myelofibrosis

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19
Q

How does teardrop RBCs come about?

A

Seen when marrow undergoes fibrosis

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20
Q

Leukoerythoblastosis is associated with?

A

Myelophthsic process

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21
Q

Blood loss gives you?

A

Reticulocytosis

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22
Q

Acute respiratory syndrome in SC is due to?

A

RBC sticking to endothelium

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23
Q

Hereiditary spherocytosis is susceptible to parovirus, you wont be able to see any __ in the blood smear?

A

reticulocytes

24
Q

beta thalassemia cause anemia by?

A

alpha chain aggregates lysing RBC in bone marrow—>hemochromatosis

25
Q

SC damaged what organ?

A

spleen

26
Q

EPO stimulate erythepoesis through?

A

Inhibition of apoptosis

27
Q

Macrocytic anemia is also called?

A

megoblastic anemia (B12/folate deficiency)

28
Q

Aplastic anemia shows increase ___ in the bone marrow?

A

Fat

29
Q

Hereiditary spherocytosis increases risks for ___?

A

Cholelithiasis (gallstone)

30
Q

What is burr cells and when do you see it?

A

Echinocytes (moderately spiky cells)—>renal failure

31
Q

What is acanthocytosis and when do you see it?

A

really spiky cells—>liver failure

32
Q

Myelodysplastic syndrome can be caused by?

A

chemo

33
Q

Schiling test is for ?

A

B12 absorption

34
Q

ITP can follow ___ of a child?

A

viral illness (self-limiting)

35
Q

EBV can cause cold of warm IHA?

A

Cold

36
Q

TTP is ___ + and cause ___ impairment?

A

PAS and renal impairment

37
Q

Vasculitis can cause the fragmentation of ?

A

RBC

38
Q

What cause macroangiopathic hemolytic anemia?

A

Mechanical sheering like prosthetic valve

39
Q

What kind of genetic pattern is Hemophilia A/B pass from gen to gen?

A

X-linked

40
Q

Suppurative lymphadenitis drains the site of?

A

acute bacterial infection

41
Q

CLL can progress to?

A

Diffuse large B cell lymphoma (Richter transformation)

42
Q

Thymoma is associated with?

A

Myasthenia gravis

43
Q

Posttransplant lymphoproliferative disorder is often associated with ?

A

immunsuppression and EBV

44
Q

What is seborrheic keratoses present microscopically?

A

Pesudocyst/broad anastomosing cords of mature stratified squamous epithelium

45
Q

Dysplastic nevus syndrome/melanoma has mutation in ___ gene?

A

CDKN2A

46
Q

Reduction of ___ is seen in ichtyosis vulgaris?

A

reduced keratohyaline granules (thin granulosum)

47
Q

When do you usually see epidermolysis bullosa?

A

At birth or shortly after (on inflammatory cells nor antibodies)

48
Q

Basophilic epithelial cells is seen in?

A

Basal cell carcinoma

49
Q

Does HPV warts bleed easily?

A

Yes

50
Q

Dermatitis herpetiformis presents as?

A

really itchy hive like vesicles

51
Q

EM is associated with __ reaction?

A

Drug (immune sensitivity)

52
Q

__ has immune complexes deposited in the endothelial vascular wall?

A

Cutaneous necrotizing vasculitis

53
Q

Allergic dermatitis sensitization phase and repeated exposure?

A

Antigen bind to langerhan cells—>langerhand cells travel lymph node and present it to T cells—>reexposure—>langerhand and T cells accumulate—>spongiosis

54
Q

PNH can proceed to?

A

AML

55
Q

Cold IHA is associated with?

A

EBV and myco prnumoniae

MSII Unit II (8 decks)

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