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MS2 Unit 2 > Robbins Q/A > Flashcards

Robbins Q/A Flashcards

1
Q

skin finding assoc with (cancers/SLE/mastocytosis/AIDS/Langerhans cell histiocytosis): acanthosis nigricans

A

cancers

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2
Q

skin finding assoc with (cancers/SLE/mastocytosis/AIDS/Langerhans cell histiocytosis): rashes that exhibit photosensitivity

A

SLE. due to antigen-antibody complex deposition

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3
Q

skin finding assoc with (cancers/SLE/mastocytosis/AIDS/Langerhans cell histiocytosis): urticaria

A

mastocytosis

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4
Q

skin finding assoc with (cancers/SLE/mastocytosis/AIDS/Langerhans cell histiocytosis): disseminated infections, papulosquamous dermatoses (not pigmented lesions)

A

AIDS

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5
Q

skin finding assoc with (cancers/SLE/mastocytosis/AIDS/Langerhans cell histiocytosis): occurs in children, produces reddish papules or nodules or erythematous scaling plaques

A

Langerhans

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6
Q

(scabies/Borrelia burgdorferi/tinea corporis/staph and strep A/molluscum contagiosum): intense pruritus, linear lesions

A

scabies

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7
Q

(scabies/Borrelia burgdorferi/tinea corporis/staph and strep A/molluscum contagiosum): erythema chronicum migrans

A

BB

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8
Q

(scabies/Borrelia burgdorferi/tinea corporis/staph and strep A/molluscum contagiosum): superficial infection, erythema and crusting

A

tinea corporis

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9
Q

(scabies/Borrelia burgdorferi/tinea corporis/staph and strep A/molluscum contagiosum): impetigo

A

staph and strep A

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10
Q

(scabies/Borrelia burgdorferi/tinea corporis/staph and strep A/molluscum contagiosum): localized, firm nodule

A

molluscum. poxvirus

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11
Q

pruritic, purple, polygonal papules

A

lichen planus

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12
Q

bandlike infiltrate of lymphocytes at the dermal-epidermal junction, self-limited, may include oral lesions

A

lichen planus

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13
Q

(keratoacanthoma/SCC/BSC/seborrheic keratosis/actinic keratosis/verruca vulgaris): keratin filled crater surrounded by proliferating epithelium, self-limiting

A

keratoacanthoma

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14
Q

(keratoacanthoma/SCC/BSC/seborrheic keratosis/actinic keratosis/verruca vulgaris): rough surfaced, pigmented lesion that slowly enlarges over time

A

seborrheic keratosis

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15
Q

(keratoacanthoma/SCC/BSC/seborrheic keratosis/actinic keratosis/verruca vulgaris): flat, pigmented, tan to brown to red

A

actinic keratosis

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16
Q

(keratoacanthoma/SCC/BSC/seborrheic keratosis/actinic keratosis/verruca vulgaris): on hands and feet, rough upper surface, comes and goes over years

A

verruca vulgaris

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17
Q

(malassezia furfur/epidermophyton and trichophyton and microsporum/HSV/HPV/mycobacterium leprae): tinea versicolor

A

malassezia furfur

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18
Q

(malassezia furfur/epidermophyton and trichophyton and microsporum/HSV/HPV/mycobacterium leprae): athlete’s foot and jock itch

A

phytons and microsporum

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19
Q

(malassezia furfur/epidermophyton and trichophyton and microsporum/HSV/HPV/mycobacterium leprae): crops of clear vesicles that may burst and form painful shallow ulcers

A

HSV

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20
Q

(malassezia furfur/epidermophyton and trichophyton and microsporum/HSV/HPV/mycobacterium leprae): condyloma acuminatum

A

HPV (genital warts)

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21
Q

(malassezia furfur/epidermophyton and trichophyton and microsporum/HSV/HPV/mycobacterium leprae): c Hansen disease, areas of skin anesthesia that predispose to repeated trauma

A

leprae

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22
Q

(epidermal inclusion cyst/fibroepithelial polyp): skin tag, acrochordon

A

fibroepithelial polyp

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23
Q

(epidermal inclusion cyst/fibroepithelial polyp): formed from downward growth of epithelium or expansion of a hair follicle, lined by squamous epithelium

A

epidermal inclusion cyst

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24
Q

(lymphoplasmacytic lymphoma/hypercalcemia/multiple myeloma/follicular lymphoma): t(14;18)

A

follicular lymphoma

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25
Q

(lymphoplasmacytic lymphoma/hypercalcemia/multiple myeloma/follicular lymphoma): Waldenstrom macroglobulinemia

A

lymphoplasmacytic lymphoma

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26
Q

(lymphoplasmacytic lymphoma/hypercalcemia/multiple myeloma/follicular lymphoma): punched-out lytic lesions

A

multiple myeloma

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27
Q

(lymphoplasmacytic lymphoma/hypercalcemia/multiple myeloma/follicular lymphoma): Russell bodies

A

lymphoplasmacytic lymphoma aka Waldenstrom macroglobulinemia

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28
Q

(lymphoplasmacytic lymphoma/hypercalcemia/multiple myeloma/follicular lymphoma): hyperviscosity, cold agglutinin

A

lymphoplasmacytic lymphoma aka Waldenstrom macroglobulinemia

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29
Q

(leukemoid rxn/CML/hairy cell leukemia/Hodgkin/ALL): high alkaline phosphatase

A

leukemoid reaction

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30
Q

(leukemoid rxn/CML/hairy cell leukemia/Hodgkin/ALL): low alkaline phosphatase

A

CML

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31
Q

(leukemoid rxn/CML/hairy cell leukemia/Hodgkin/ALL): Philadelphia chromosome

A

CML

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32
Q

(leukemoid rxn/CML/hairy cell leukemia/Hodgkin/ALL): peripheral blood leukocytes that mark with tartrate-resistant acid phosphatase

A

hairy cell

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33
Q

(leukemoid rxn/CML/hairy cell leukemia/Hodgkin/ALL): not characterized by high WBC count

A

Hodgkin

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34
Q

(leukemoid rxn/CML/hairy cell leukemia/Hodgkin/ALL): disease of children and young adults, and lymphoid cells do not have leukocyte alkaline phosphatase

A

ALL

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35
Q

(diffuse large B-cell lymphoma/lymphoblastic lymphoma/Hodgkin/chronic lymphadenitis/non Hodgkin lymphoma): monomorphorous infiltrate

A

non Hodgkin

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36
Q

(diffuse large B-cell lymphoma/lymphoblastic lymphoma/Hodgkin/chronic lymphadenitis/non Hodgkin lymphoma): lymph node has macrophages, lymphocytes, plasma cells

A

chronic lymphadenitis

37
Q

(diffuse large B-cell lymphoma/lymphoblastic lymphoma/Hodgkin/chronic lymphadenitis/non Hodgkin lymphoma): Reed Sternberg cells

A

Hodgkin

38
Q

(diffuse large B-cell lymphoma/lymphoblastic lymphoma/Hodgkin/chronic lymphadenitis/non Hodgkin lymphoma): T cell neoplasm in mediastinum of children

A

lymphoblastic lymphoma

39
Q

(diffuse large B-cell lymphoma/lymphoblastic lymphoma/Hodgkin/chronic lymphadenitis/non Hodgkin lymphoma): Waldeyer ring involved

A

diffuse large B cell

40
Q

(diffuse large B-cell lymphoma/lymphoblastic lymphoma/Hodgkin/chronic lymphadenitis/non Hodgkin lymphoma): staining pattern indicates B cell prolif (CD19 and CD10)

A

diffuse large B cell

41
Q

(diffuse large B-cell lymphoma/lymphoblastic lymphoma/small lymphocytic lymphoma/Hodgkin/chronic lymphadenitis/non Hodgkin lymphoma): B cell neoplasm with widespread lymphadenopathy, hepatosplenomegaly, lymphocytosis

A

small lymphocytic lymphoma

42
Q

(diffuse large B cell lymphoma/myeloid leukemia/myelodsyplasia/myeloid metaplasia): maturation defects in multiple lineages in the marrow. ringed sideroblasts in the marrow

A

myelodysplasia

43
Q

(diffuse large B cell lymphoma/myeloid leukemia/myelodsyplasia/myeloid metaplasia): 5q deletion

A

post therapy myelodysplasia

44
Q

(CML/myelofibrosis/polycythemia vera/AML/essential thrombocytopenia): throbbing, burning pain in hands and feet caused by platelet aggregates occluding arterioles

A

essential thrombocytopenia

45
Q

(CML/myelofibrosis/polycythemia vera/AML/essential thrombocytopenia): WBC count high, without thrombocytosis

A

AML

46
Q

(CML/myelofibrosis/polycythemia vera/AML/essential thrombocytopenia): myeloproliferative disorder, dominant cell type affected is megakaryocyte, thrombocytosis

A

essential thrombocytopenia

47
Q

eosinophilia suggests what type of infection: (viral/bacterial/parasitic)

A

parasitic (ex. strongyloidiasis)

48
Q

(ALL/multiple myeloma/Letterer-Siwe/myelodysplastic syndrome/peripheral T cell lymphoma or leukemia): Birbeck granules

A

Letterer-Siwe (form of Langerhans cell histiocytosis)

49
Q

(ALL/multiple myeloma/Letterer-Siwe/myelodysplastic syndrome/peripheral T cell lymphoma or leukemia): lymphoblasts that mark as T cells in thymic masses in children

A

ALL

50
Q

(ALL/multiple myeloma/Letterer-Siwe/myelodysplastic syndrome/peripheral T cell lymphoma or leukemia): plasma cells, older adults, monoclonal gammopathy

A

multiple myeloma

51
Q

(ALL/multiple myeloma/Letterer-Siwe/myelodysplastic syndrome/peripheral T cell lymphoma or leukemia): ringed sideroblasts

A

myelodysplastic syndrome

52
Q

(ALL/multiple myeloma/Letterer-Siwe/myelodysplastic syndrome/peripheral T cell lymphoma or leukemia): Sezary cells

A

peripheral T cell lymphoma

53
Q

(AML/bacterial sepsis/G6PD def/hairy cell leukemia): Auer rods, which are condensations of azurophilic granules

A

AML

54
Q

(AML/bacterial sepsis/G6PD def/hairy cell leukemia): Dohle bodies (dilated ER)

A

bacterial sepsis

55
Q

(AML/bacterial sepsis/G6PD def/hairy cell leukemia): projections on circulating B cells

A

hairy cell leukemia

56
Q

(AML/bacterial sepsis/G6PD def/hairy cell leukemia): Heinz bodies, precipitates of denatured Hb

A

G6PD def

57
Q

(chronic infection/acute viral hepatitis/glucocorticoids/vigorous exercise/AML): can lead to expansion of myeloid precursor pool in marrow > neutrophilic leukocytosis

A

chronic infection

58
Q

(chronic infection/acute viral hepatitis/glucocorticoids/vigorous exercise/AML): can increase release of marrow storage pool cells and diminish extravasation of neutrophils into tissues

A

glucocorticoids

59
Q

(chronic infection/acute viral hepatitis/glucocorticoids/vigorous exercise/AML): can produce neutrophilia from demargination of neutrophils

A

exercise

60
Q

(chronic infection/acute viral hepatitis/glucocorticoids/vigorous exercise/AML): marrow is filled with blasts

A

AML

61
Q

(CML/Burkitt lymphoma/follicular lymphoma): t(8;14)

A

Burkitt

62
Q

(CML/Burkitt lymphoma/follicular lymphoma): t(14;18)

A

follicular lymphoma

63
Q

SLE can be accompanied by (eosinophilia/thrombocytosis/monocytosis/neutrophilia/basophilia)

A

monocytosis

64
Q

area endemic for HTLV-1

A

Japan

65
Q

undetectable EPO, increased Hct and blood volume

A

polycythemia vera

66
Q

cerebriform nuclei found in ______

A

cutaneous T cell lymphomas such as mycosis fungoides, Sezary syndrome

67
Q

(IgG/IgM) coating RBCs: cold agglutinin disease

A

IgM

68
Q

(IgG/IgM) coating RBCs: warm antibody hemolytic anemia

A

IgG

69
Q

increase in hemoglobin A2 in: (iron def anemia/autoimmune hemolytic anemia/beta thalassemia minor)

A

beta thalassemia minor

70
Q

MCC of iron def anemia in elderly: (pernicious anemia/GI blood loss/menstruating)

A

GI blood loss (carcinoma, ulcers)

71
Q

pernicious anemia from B12 deficiency: (micro/macro) cytic anemia

A

macro

72
Q

(iron deficient anemia due to bleeding malignancy/autoimmune hemolytic anemia/thalassemia/chronic alcoholism/Vit B12 def/Hemophilia A): microcytic and hypochromic anemia

A

iron def due to occult malignancy

73
Q

(iron deficient anemia due to bleeding malignancy/autoimmune hemolytic anemia/thalassemia/chronic alcoholism/Vit B12 def/Hemophilia A): normocytic anemia with pronounced reticulocytosis

A

autoimmune hemolytic anemia

74
Q

(iron deficient anemia due to bleeding malignancy/autoimmune hemolytic anemia/thalassemia/chronic alcoholism/Vit B12 def/Hemophilia A): microcytosis, severe anemia soon after birth

A

thalassemia

75
Q

(iron deficient anemia due to bleeding malignancy/autoimmune hemolytic anemia/thalassemia/chronic alcoholism/Vit B12 def/Hemophilia A): macrocytosis due to folate def

A

alcoholism

76
Q

(iron deficient anemia due to bleeding malignancy/autoimmune hemolytic anemia/thalassemia/chronic alcoholism/Vit B12 def/Hemophilia A): joint problems because bleeding is mainly into soft tissues without blood loss

A

hemophilia A

77
Q

(iron deficient anemia due to bleeding malignancy/autoimmune hemolytic anemia/thalassemia/chronic alcoholism/Vit B12 def/Hemophilia A): macrocytic anemia (two diseases)

A

chronic alcoholism and Vit B12 def

78
Q

(iron def anemia/aplastic anemia/microangiopathic hemolytic anemia/anemia of chronic dz/megaloblastic anemia): increased ferritin concentration and reduced total iron-binding capacity

A

chronic disease

79
Q

(iron def anemia/aplastic anemia/microangiopathic hemolytic anemia/anemia of chronic dz/megaloblastic anemia): caused by serious acute conditions such as DIC

A

microangiopathic hemolytic anemia

80
Q

(iron def anemia/aplastic anemia/microangiopathic hemolytic anemia/anemia of chronic dz/megaloblastic anemia): thrombocytopenia caused by widespread thrombosis

A

microangiopathic hemolytic anemia

81
Q

(iron def anemia/aplastic anemia/microangiopathic hemolytic anemia/anemia of chronic dz/megaloblastic anemia): pancytopenia and absence of reticulocytosis

A

aplastic anemia

82
Q

acute blood loss leads to: (schistocytes/basophilic stippling/reticulocytosis/leukoerythroblastosis)

A

reticulocytosis. blood loss results in marrow stimulation by anemia, leading to reticulocytosis

83
Q

paroxysmal nocturnal hemoglboinuria: (spectrin/G6PD/PIGA/Factor V/Beta globin chain) mutation

A

PIGA

84
Q

(ITP/von Willebrand dz/Factor V mutation/Hemophilia A with factor VIII inhibitor/DIC): XLR, bleeding into joints, PTT is prolonged

A

Hemophilia A with factor VIII inhibitor

85
Q

(ITP/von Willebrand dz/Factor V mutation/Hemophilia A with factor VIII inhibitor/DIC): recurrent thromboses

A

factor V mutation

86
Q

(ITP/von Willebrand dz/Factor V mutation/Hemophilia A with factor VIII inhibitor/DIC): acute condition resulting from an underlying dz, platelets are consumed

A

DIC

87
Q

(ITP/von Willebrand dz/Factor V mutation/Hemophilia A with factor VIII inhibitor/DIC): platelet count, PT and PTT are all normal. Decreased platelet adherence

A

von Willebrand disease

88
Q

(ITP/von Willebrand dz/Factor V mutation/Hemophilia A with factor VIII inhibitor/DIC):autoimmune condition with thrombocytopenia leading to bleeding

A

ITP

MS2 Unit 2 (9 decks)

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