RNA - Viruses Flashcards by Sophia Skedros | Brainscape

Q

All - RNA viruses must

A

Bring their own RNA polymerase

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Q

All RNA viruses are SS except

A

Reoviridae

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Q

What’s special about orthomyxovirus

A

It replicates in the nucleus

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Q

Segmented viruses

A

BOAR

B=bunyavirus
O=orthomyxo
A=arenavirus
R=reovirus

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Q

Most flu cases due to

A

Influenza A and B

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Q

A subtypes based on antigenicity of

A

Hemagglutinin and Neuramidase

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Q

HA mediates

A

Cell fusion

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Q

HA needs _____ gets them ____ so it doesn’t fuse @_____

A

Proteolytic cleavage and low pH

Endosome s

Plasma membrane

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Q

NA promotes

A

Spread of virus

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Q

M2 is responsible for

A

Uncoating

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Q

Drift associated with

A

Epidemic
Point mutations in HA and NA

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Q

Shift associated with

A

Pandemics
Reassortment of HA and NA

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Q

Where does reassorment usually occur

A

Intermediate hosts

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Q

___ allows influenza to pass from person to person

A

Adaptation

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Q

Where does influenza adapt

A

In intermediate host or directly in humans

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