Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

I And I Final > RNA + Viruses > Flashcards

RNA + Viruses Flashcards

1
Q

Pico virus sketchy scene

A

Peak orna animal nursery

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Naked, icosahedral, +ssDNA, small

A

Pico

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

All + sense get replicated

A

In cytoplasm

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Polio transmission

A

Resp and fecal/oral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Polio can cross

A

BBB

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Infects axons of peripheral nerves and attacks anterior horn of spinal cord

A

Polio

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Most kids with _____ are asymptomatic

A

Polio

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What percent of polio is severe

A

1-2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Paralysis of diaphragm

A

Polio

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What are all the enteroviruses

A

Polio
Coxsackie
Echovirus
Enterovirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Enteroviruses are stable at _____ pH

A

Acidic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Enteroviruses replicate in

A

Oropharynx and GI tract

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Enterovirus 71 causes

A

Hand foot and mouth
Poliomyelitis
Not really in USA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Enterovirus D68 causes

A

Acute flaccid myelitis
a resp illness comes before this

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Encephalomyocarditis syndrome

A

Coxsackie B1 virus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Acid labile +

A

Rhino

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Major trigger of asthma exacerbations and development of childhood asthma

A

Rhino

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

How does hep A transmit

A

Contaminated food
Fecal oral - daycares
IV drug use - #1 in USA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Jaundice, abnormal liver enzymes, fever, fatigue, nausea, abdominal discomfort

A

Hep A

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Leading cause of viral gastroenteritis over all age groups

A

Norovirus - caliciviridae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Food preparer who is no longer symptomatic can still transmit virus

A

Norovirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Low infectious dose, naked, fecal/oral transmission, common in daycares

A

Norovirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Enveloped, iscosahedaral, arbovirus

A

Flaviviridae

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

If you have an antibody for yellow fever what could you also be protected agains

A

Dengue
Yellow
Zika
WN
Japanese encephalitis
St. Louis encephalitis
Powassan

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What are the primary targets for flaviviridae

A

Cells of monocyte and macrophage lineage
Also dendritic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

May infect endothelial cells of capillaries, has glycoproteins E1 and E2

A

Flavivir

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Breakbone fever

A

Dengue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Worldwide, especially tropics

A

Dengue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Africa, South America

A

Yellow fever

30
Q

Zika

A

Worldwide, especially tropics

31
Q

Asia

A

Japanese encephalitis

32
Q

Africa, Europe, Central Asia, North America

33
Q

North America

A

St. Louis encephalitis
And
Powassan encephalitis

34
Q

Sylvatic vs urban

A

S = wooded areas
primate —> mosquito—>human

U = human—>mosquito—>human

35
Q

Gets midgut of ____ and moves to their ____ glands

A

Mosquito

Salivary

36
Q

Arboviruses are picked up through the ___ but spread through ____

A

Blood

Saliva

37
Q

With arbovirus, if virus is not cleared after primary viremia what can happen

A

Secondary viremia can produce enough virus to infect other organs

38
Q

Mild affects of arbovirus primary viremia

A

Fever, chills, headaches, arthralgias

39
Q

Effects of secondary arbovirus viremia

A

Hemorrhagic feve
Shock
Encephalitis

40
Q

Assembly and release of HCV

A

HCV and VLDL form lipo viral particle

The viral antigens in LVP are shielded form immune response

41
Q

Flushed skin, red conjunctiva, hepatomegaly

42
Q

Yellow fever presentation

A

Infection—>remission—>intoxication—>death

43
Q

Intoxication YFV

A

High fever
Coagulopathy and hemorrhaging
Hepatic is wack/jaundice
Renal failure
Shock

44
Q

If you’re going to Africa or South America what should you get

A

YFV live vax

45
Q

Retro-orbital pain

46
Q

Describe the antibody - dependent enhancement
Which disease

A

Dengue

1st infection: our body makes Ab to the infecting subtype

2nd infection: the 1Ab can cross react and bind to the 2nd infecting subtype. This enhances the uptake of the virus bc the virus has FC receptor

47
Q

Why can Zika be scary

A

Congenital Zika = microencephaly

Guillain barre

48
Q

Chronic inflammatory demyelinating polyneuropathy

49
Q

What are the encephalitis viruses

A

West Nile, St. Louis, Powassan

50
Q

Presentations of encephalitis viruses

A

Non-neuroinvasive

Neuroinvasive

51
Q

Intermediate host for MERS

52
Q

Largest RNA virus

A

Coronavirus

53
Q

What binds to ACE2

A

Spike protein

54
Q

Vax for sars cov2 induces antibodies to what

A

Spike protein

55
Q

MERS transmission

A

Person to person
Doesn’t spread well

56
Q

Which is more pathogenic SARSCOV or SARSCOV2

57
Q

Why is SARSCOV2 more widespread and severe

A

Bc its less virulent so its harder to detect, people spread it easier

Mutates quick

58
Q

ARDS = ___
From what disease

A

Acute respiratory distress syndrome
Covid

59
Q

When do viral titers peak in covid

A

4 days after onset

60
Q

Describe Multisystem inflammatory syndrome what is it from

A

Cytokine storm like
heart, and kidney stuff
COVID

61
Q

SARS COV2 is huge so it has its own

A

Proofreading system

62
Q

Explain the variants of COV2

A

1: RNA polymerases make a lot of mistakes
2: recombination happens
3: this might change pathogenicity
4: which might make it easier to escape immune response
If we get OG variant our body makes Ab for OG. If we then get delta variant we do not already have the Ab for it

63
Q

Things in α genus of toga

A

EEEV
WEEV
VEEV
Chikungunya

64
Q

Toga altered pattern

A

+ RNA —> nonstructural proteins encoded in 5’ end of genomic RNA —-> - strand—-> subgenomic + mRNA from 3’ end——> structural proteins

65
Q

α virus that’s north & South America and Caribbean

66
Q

α virus that’s North & South America

67
Q

α virus that’s north, south and Central America

68
Q

α virus that’s africa and Asia

A

Chikungunya

69
Q

Which α virus causes severe encephalitis

70
Q

Severity of congenital rubella depends on

A

Fetal age at time of viremia

Major risk up until 20th week of pregnancy

I And I Final (5 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions