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Microbiology > RNA Virus > Flashcards

RNA Virus Flashcards

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1
Q

Positive Strand Icosahedral Naked RNA Virus

A

Picornaviridae
Caliciviradae

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2
Q

Positive Strand Icosahedral Enveloped RNA Virus

A

Flaviviridae
Retroviridae
Togaviridae

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3
Q

Positive Strand Helical Enveloped RNA Virus

A

Coronaviridae

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4
Q

Caused by Polio virus

A

Poliomyelitis

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5
Q

Attacks lower motor neurons of CNS resulting to flaccid paralysis

A

Poliomyelitis

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6
Q

Transmission of Poliovirus

A

Ingestion of water (Feces)

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7
Q

Primary site of Polio Virus

A

Peyer’s Patches

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8
Q

Prevention of Poliovirus

A

Salk - killed virus, IM
Sabin - live attended virus (oral)

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9
Q

Hand, foot, mouth disease

A

Coxsackievirus A

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10
Q

Cause Viral Heart Disease, pleurodynia; pericardis; myocarditis

A

Coxsackie B Virus

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11
Q

Meningoencephalitis

A

Coxsackie A and B Virus

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12
Q

Hepatovirus

A

Hepatitis A Virus

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13
Q

Hepatitis A Virus

A

Infectious Hepatitis

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14
Q

Human Rhinovirus

A

Common Colds

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15
Q

Calici virus

A

Norwalk Virus

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16
Q

Major cause of nonbacterial epidemic gastroenteritis worldwirde

A

Norwalk Virus

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17
Q

Flaviviridae/Flavivirus ⭐

A

Dengue fever Virus
St. Louis Encephalitis Virus
Zika Virus

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18
Q

Dengue fever

A

Breakbone fever

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19
Q

Vector of Dengue Virus

A

Aedes aegypti Mosquito ⭐

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20
Q

Severe disease caused by dengue fever

A

Dengue Hemorrhagic Fever

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21
Q

DOH program for Dengue

A

4 o’clock habit ⭐

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22
Q

Vaccine for Dengue Virus

A

CYD-TDV (Dengvaxia) ⭐
Tetravalent, live attenuated, chimeric dengue vaccine
3 dose, 6 months apart
Manufacture by: Sanofi-Pasteur ⭐

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23
Q

Clinical Phase of Dengue Fever

A

1) Febrile Phase – occurs below D2 – D7 of illness
(2) Critical Phase – occurs at D5 – D6 of illness; signs and symptoms include: plasma leakage; bleeding; severe organ involvement; can last for 24 – 48 hours
(3) Convalescence Period – recovery phase

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24
Q

Vector of St. Louis Encephalitis Virus

A

Culex mosquitoes

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25
Q

Most important reservoir of St. Louis Encephalitis Virus

A

Wild Birds

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26
Q

Vector of Zika Virus

A

Aedes aegypti
Aedes albopictus

27
Q

Autoimmune disorder that is associated with Zika Virus

A

Guillain-Barre Syndrome

28
Q

Infection with Zika Virus during pregnancy leads to

A

Microencephaly

28
Q

Infection with Zika Virus during pregnancy leads to

A

Microencephaly

29
Q

Retroviridae

A

HIV-1 & 2
Huamn T Lymphotropic Virus

30
Q

Human Immunodeficiency virus (HIV)

A

Attacks CD4 T-Helper Cells

31
Q

Enzyme found in HIV

A

Reverse transcriptase

32
Q

Human T Lymphotropic Viruses

A

Adult T Cell leukemia

33
Q

Togaviridae

A

Rubivirus - Rubella Virus
Alphavirus - Chinkungunya Virus

34
Q

Rubella Virus

A

German measle
3-Day measles

35
Q

First detected in Saudi Arabia in 2012

A

Merscov

36
Q

Reservoir Host of Merscov

A

Camel

37
Q

Posses distinctive arrangements of spikes (peplomers) on the viral surface; Crown-like

A

Coronaviridae

38
Q

Disease associated with SARS-COV 2

A

COVID-19

39
Q

Transmission of SARS-COV 2

A

Respiratory Droplets
Fomites
Aerosols

39
Q

Transmission of SARS-COV 2

A

Respiratory Droplets
Fomites
Aerosols

40
Q

Negative, Single Stranded Helican Enveloped RNA Virus

A

Orthomyxoviridae
Paramyxoviridae
Rhabdoviridae
Filoviridae

41
Q

Orthomyxoviridae

A

Influenza Virus
A(H1N1) Virus
A(H5N1) Virus
A(H7N9) Virus

42
Q

Glycoproteins in envelope of Influenza

A

Hemogglutinin, Nerominidase

43
Q

Antigenic Drift

A

Small Mutations/Changes
Changes to surface of Hemogglutinin, Nerominidase
Accumulate over time result in viruses that are antigenically different happens in an important location

44
Q

Antigenic Shift

A

Mutations or changes are abrupt
Result to New hemogglutinin, Nerominidase protein
New influenza A subtype
Result to Pandemic

45
Q

A(H1N1) Virus

A

Swine Influenza/Swine Flu

46
Q

Mixing vessel of A(H1N1)

A

Pigs

47
Q

A(H5N1) Virus and A(H7N9) Virus

A

Bird Flu/Avian Flu

48
Q

Treatment of A(H5N1) Virus and A(H7N9) Virus

A

Ozeltamivir

49
Q

Paramyxoviridae

A

Parainflenza virus
Mumps virus
Rubeola Virus

50
Q

Mumps Virus

A

Aka: Infectious Parotitis (Parotid salivary gland)
Complication: Orchitis

51
Q

Rubeola Virus

A

Hard measles
S/S: Maculopapular Rash, Koplik’s spots

52
Q

Bullet – shaped viruses w/ a spiked envelope

A

Rhabdoviridae - Rabies virus

53
Q

Most common reservoirs of Rabies

A

Dogs

54
Q

Disease caused by Rabies Virus

A

Acute, fulminant fatal encephalitis

55
Q

Diagnosis of Rabies

A

Negribodies - Aggregates of virus in the brain of animals

56
Q

FIloviridae

A

Ebola Virus
Marburg Virus

57
Q

Ebola Virus

A

Ebola Virus Disease
Ebola Hemorrhagic Fever

58
Q

Animal Reservoir of Ebola Virus

A

Bats

59
Q

Transmission of Ebola Virus

A

Sexual Contact
Fomites
Bloody body fluids
Direct contact with wild animals

60
Q

Rotavirus

A

Double-Stranded, Icosahedral Naked Reviridae
Cause of infantile gastroenteritis

61
Q

Strains of Ebola Virus

A

a. Zaire & Sudan – most virulent; 2014 West Africa Outbreak
b. Tail Forest
c. Bundibugyo
d. Reston – found in Philippines and China; sourced from Philippine Macaque Monkey; does not cause disease in humans; disease in swines/pigs

Microbiology (17 decks)

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