Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

CMB > RNA Metabolism > Flashcards

RNA Metabolism Flashcards

1
Q

What structure can RNA molecules fold into?

A

Bulge,Internal Loop, Hairpin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Order the types of RNA from most to least common?

A

rRNA, tRNA, mRNA other forms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Describe the Process of Transcriptional Initiation in E. Coli

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Describe the Process of Initiation at RNA Pol I?

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Describe the initiation process at RNA Pol III

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Process of Initiation at RNA Pol II

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Actinomycin: Action and Mechanism

A

Intercalates between G and C residues

inhibits transcriptional elongation in pro and eukaryotes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Rifampicin: Action and Mechanism

A

binds the beta subunit of bacterial RNA polymerase

blocks promter clearance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Aplha amanitin

A

comes from a death cap mushroom

inhibits RNA pol II greatly and is a weak inhibitor of RNA pol III

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Draw the Nuclear Splicing Mechanism

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Describe the processing of 3’ mRNA

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

rRNA processing in Eukaryotes

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

rRNA processing in Prokaryotes

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

tRNA processing

A
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What occurs in the initiation, elongation, and termination sequences of RNA pol II?

A

Initiation occurs after phosporylation of the C-terminal domain of RNA Pol II by TFIIH

Elongation begins after the synthesis of the initial 60-70 ribonucleotides when TFIIE and TFIIH are kicked off and elongation factors bind

Termination starts with polyadenylation or 3’ end formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is the secondary action of TFIIH?

A

TFIIH is involved in transcription coupled DNA-repair subunits of TFIIH interact with the encountered lesion and recruit the whole nucleotide exision repair complex

17
Q

What are the post transcriptional modifications done to rRNA, mRNA and tRNA respectively?

A

rRNA - methylation, nucleolytic cleavage

mRNA - 5’ cap, polyadenylation, removal of introns (nuclear splicing)

tRNA - 5’ and 3’ cleavage, CCA addition, base modification, tRNA splicing

CMB (12 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions