Developmental Genetics Flashcards
1
Q
What are some problems caused by damage to GLI3?
A
Greig Cephalopolysyndactly
Pallister-Hall syndrome
limb, central nervous system, craniofacial, airway and genitourinary defects
2
Q
What does damage to the PTCH receptor cause?
A
GPCS with dental cysts basal cell carcinoma not as much limb problems
3
Q
What are problems associated with damage to CREB?
A
CREB is a transcriptional coactivator for CHD so it causes
Rubenstein Taybi syndrome which is GCPS with mental retardation and
