Developmental Genetics Flashcards

1
Q

What are some problems caused by damage to GLI3?

A

Greig Cephalopolysyndactly
Pallister-Hall syndrome
limb, central nervous system, craniofacial, airway and genitourinary defects

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2
Q

What does damage to the PTCH receptor cause?

A

GPCS with dental cysts basal cell carcinoma not as much limb problems

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3
Q

What are problems associated with damage to CREB?

A

CREB is a transcriptional coactivator for CHD so it causes

Rubenstein Taybi syndrome which is GCPS with mental retardation and

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