Risk factors. Primary and secondary preventions Flashcards

1
Q

Primary prevention

A
  • goal: prevent coronary and cerebrovascular disease in people at risk
  • main tool: lifestyle changes
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2
Q

Secondary prevention

A
  • goal: prevent further events, attempt to slow the progression and improve the general quality of life. Decrease the need for interventional procedures
  • tools: lifestyle + drugs
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3
Q

Primary risk factors:

A
  • modifiable RF: Smoking, HTN, Hyper/Dyslipidemia, DM, Obesity
  • Non-modifiable RF: Age, Gender, Genetics
  • Other RF: Alcohol, Exercise, diet, uric acid and homocysteine levels
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4
Q

What is the SCORE system

A

Systematic Coronary Risk Evaluation system: SCORE system
- is a High & Low cardiovascular Risk Charts based on gender, age, total cholesterol, systolic blood pressure and smoking status, with relative risk chart, qualifiers and instructions

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5
Q

Cardiovascular effects of DM

A
  • increases plasma coagulation
  • altered response to injured artery
  • decreased fibrinolysis
  • decreased endothelial thrombotic resistance
  • platelet hypercoagulopathy
  • goal in DM patients is to keep the HbA1c < 7%
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6
Q

Effects of smoking on cardiovascular system

A
  • increases BP and HR
  • platelet activation and thromboembolism
  • endothelial dysfunction
  • coronary spasms
  • increases LDL, decreases HDL
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7
Q

BP control

A
  • goal in DM patients: 140/90 mmHg
  • goal in chronic kidney disease: 130/80 mmHg
  • drugs: ACEi, ARB, Ca blocker, Diuretics, BB
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8
Q

Lipid management

A
  • LDL < 1.8M, use statins
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9
Q

Benefits of physical activity

A
  • decrease cardiovascular disease
  • decreased risk of DM
  • decrease HTN
  • decrease colon cancer
  • weight control
  • strenght
  • decrease anxiety
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10
Q

Weight management

A
  • keep BMI: 18.5 - 24.9 kg/m2

- Wast: M<102cm, W<88cm

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11
Q

State the anti platelet drugs

A
  • clopidogrel, ticagrelor -> inhibits ADP binding platelet
  • Dipyridamole -> inhibits PDE
  • Aspirin (COX inhibitor) -> inhibits thromboxane synthesis
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12
Q

Hospital discharge medication for Acute coronary Syndrome

A
  • aspirin, clopidogrel: antiplaletes
  • beta blockers: anti-arrhythmics
  • statins: for the lipid management
  • ACEi
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13
Q

A-fib drugs

A
  • Warfarin to INR 2-3
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