Risk Factors For Arterial Thrombosis

Question 1

Describe the Three Risk Factors For Arterial Thrombosis

Answer 1

1. Atherosclerosis
2. Platelet Hypersensitivity
3. HIV Infection

Question 2

Describe the risk factors associated with the development of Atherosclerosis.

Answer 2

Cigarette smoking, physical inactivity, obesity, hypertension, dyslipidaemia (imbalance of lipids), hyperhomocysteinaemia, male sex, menopause and metabolic syndrome

Question 3

Describe platelet hypersensitivity

Answer 3

Platelet hypersenstitivity is the tendency to aggregate in response to much lower agonsit concentrations than would be normally required.

after the atherosclerotic plaque, platelet hypersensitivity is responsible for the final occluding event

remember that arterial thrombi tends to be platelet rich and platelet driven

Question 4

Describe the markers for Arterial disease

Answer 4

1. PAI-1
2. Plasma Fibrinogen