Rhonda Patrick Flashcards
How many replication errors occur due to the imperfection of DNA/RNA polymerases per cell division?
120,000 sequence errors per replication
99% of the errors are corrected by the polymerases
Why is colon cancer more common than Duodenum cancer?
More cell divisions there. Colon 10x more divisions per lifetime.
What is magnesium so important?
it affects the efficiency of DNA polymerase enzymes. (error and repair)
Eat chlorophyll containing leafy greens.
What is the suprachiasmatic nucleus?
Master clock that influences circadian rhythms.
What does melatonin do?
Shuts down/(and initiates?) certain metabolic activities
What occurs among people that make more melatonin (like blind people)?
Less cancer
What is Beta Amyloid
Potentially harmful protein involved in Alzheimer’s
What is the importance of the medial prefrontal cortex?
It generates slow wave sleep that helps clears out amyloid beta. (a feedback loop begins in which more amyloid beta impairs slow wave sleep.)
