Rheumatology: Muscles Flashcards
1
Q
What are polymyositis and dermatomyositis?
A
Polymyositis is an idiopathic myopathy than causes symmetrical proximal muscle weakness. Dermatomyositis is similar but also has cutaneous manifestations
2
Q
How do patients with polymyositis/dermatomyositis present?
A
Symmetrical, proximal muscle weakness in the upper and lower extermities
Dysphagic can occur
Interstitial lung disease
3
Q
How do you diagnose polymyositis/dermatomyositis?
A
Raised inflammatory markers
High CK
Autoantibodies ANA, Anti Jo1 and SRP
Muscle biopsy - shows signs of inflammation, necrosis and regeneraton
4
Q
How is polymyositis/dermatomyositis managed?
A
Steroids
Methotrexate/Azathioprine