Rheumatology Final Flashcards

1
Q

Which TB drug causes Drug induced Lupus?

A

Isoniazid

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2
Q

First Line IV antibiotic for septic arthritis:

A

Flucloxacillin

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3
Q

Which should be given to patients who will be given long term steroids?

A

Immediate Alendronate

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4
Q

Blue Sclera is associated with ?

A

Osteogenesis Imperfecta

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5
Q

Pencil in Cup appearance is associated with ?

A

Psoriatic Arthritis

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6
Q

Which drug is used for SLE during Pregnancy?

A

Azathioprine

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7
Q

What is required before starting Hydroxychloroquine?

A

Examination by ophthalmologist since the drug is associated with retinopathy

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8
Q

Juxta Articular Osteoporosis is a feature of?

A

Rheumatoid Arthritis

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9
Q

Isoniazid can cause which disease?

A

SLE

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10
Q

Which antibody can be used to rule out SLE?

A

ANA since 99% of SLE patients are ANA positive

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11
Q

What is a side effect common to Azathioprine and Allopurinol?

A

Bone Marrow Supression

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12
Q

What can be used to support a diagnosis of Ankylosing Spondylitis?

A

Pelvic XRay

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13
Q

An Autoimmune disease affecting proximal muscles wit normal Creatine Kinase:

A

Polymyalgia Rheumatica

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14
Q

What is Schober’s Test ?

A

A test that measures lumbar flexion used in Ankylosing Spondylitis

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15
Q

Which tumor is associated with a sunburst pattern?

A

Osteosarcoma

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16
Q

Which tumor would show an onion skin appearance?

A

Ewing’s’ Sarcoma

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17
Q

Which tumor presents as a benign overgrowth on the skull?

A

Osteoma

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18
Q

Which tumor presents as a cartilage capped bony projection?

A

Osteochondroma

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19
Q

Which tumor presents as a double bubble / Soap bubble ?

A

Giant Cell Tumor

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20
Q

What does an X Ray of the pelvis in Ankylosing Spondylitis Show?

A

Sacroilitis

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21
Q

Systemic Sclerosis Antibody (Central):

A

Anti-Centromere

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22
Q

Which Drugs can cause Lupus?

PIMPH

A
Procainamide
Hydralazine
Isoniazid
Minocycline
Phenytoin
(PIMPH)
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23
Q

Diffuse Scleroderma Antibodies:

A

Anti-SCL-70

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24
Q

Which drug is used for Acute Gout?

A

Colchicine

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25
Q

Allergic Contact Dermatitis is type?

A

IV

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26
Q

SLE is Hypersensitivity type?

A

III

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27
Q

Sudden Stroke with elevated APTT is due to ?

A

Antiphospholipid Syndrome

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28
Q

First Line for OA?

A

Paracetamol (NSAID)

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29
Q

Rough Red papules over the knuckles are called?

A

Gottron’s Papules

Dermatomyositis

30
Q

Pain on wrist extension against resistance with elbow extended:

A

Lateral Epicondylitis

31
Q

Temporal Arteritis is associated with which AI condition?

A

PMR

32
Q

Which DMARD drug should be prescribed with caution?

A

Sulfasalazine

People allergic to aspirin might be allergic to it

33
Q

Which drug should not be prescribed with Methotrexate to avoid BM Supression?

A

Trimethoprim

34
Q

Behcets Triad

A

Oral Ulcers + Genital Ulcers + Anterior Uveitis

35
Q

Urethritis + Arthritis + Conjunctivitis :

A

Reactive Arthritis

36
Q

First line of treatment in Ankylosing Spondylitis:

A

NSAID

37
Q

Which Drug is used in the acute phase of gout?

A

NSAID (Naproxen)

38
Q

Chondrocalcinosis is a feature of ?

A

Pseudo gout

39
Q

Antiphospholipid Syndrome therapy:

A

Lifelong Warfarin

40
Q

Gout Crystals Description

A

Needle Shape

Negative Birefringence

41
Q

Presentation of RA but with involvement of DIP:

A

Psoriatic Arthritis

42
Q

Which joint isn’t involved in RA?

A

DIP

43
Q

Which Joint isn’t involved in OA?

A

MCP

44
Q

Anti-CCP are associated with ?

A

RA

45
Q

Therapy for Ankylosing Spondylitis:

A

NSAIDs + Exercise

46
Q

What distinguishes Pseudo gout from Gout?

A

Chondrocalcinosis in Pseudo Gout

47
Q

Old male wit bone pain and elevated ALKP

A

Paget

48
Q

Marfan’s inheritance Pattern:

A

Autosomal Dominant

49
Q

Felty Syndrome:

A

RA + Splenomegaly + Decreased WBC

50
Q

Limited Systemic Sclerosis syndrome;

A

CREST

51
Q

What has to be checked before using azathioprine?

A

TPMT

52
Q

Which tendonitis is associated with Ankylosing Spondylitis?

A

Achilles

53
Q

What should you monitor during hydroxychloroquine prescription?

A

Visual Acuity

54
Q

Sjogren Antibodies:

A

Anti-Ro / Anti-La

55
Q

Key investigation in PMR?

A

ESR & CRP

CK is normal

56
Q

Diffuse vs Systemic Sclerosis

A

Diffuse is associated with trunk and proximal limbs

57
Q

Ossification of outer fibers of annulus Fibrosis in Ankylosing Spondylitis:

A

Syndesmophytes

58
Q

Schirmer Test:

A

Dry Eye test

59
Q

How can you assess for Hypermobility?

A

Beighton Score

60
Q

How can you manage acute flares of RA?

A

IM Steroids

61
Q

Which antibodies are seen in drug induced lupus?

A

Anti-Histone Antibodies

62
Q

Bone changes in Ankylosing Spondylitis:

A

Subchondral Erosions / Sclerosis

63
Q

Antiphospholipid Syndrome Antibodies:

A

Anti-Cardiolipin

64
Q

PMR treatment:

A

Corticosteroids

65
Q

Antisynthetase Syndrome

A

Anti-JO1

Dermatomyositis + ILD

66
Q

Bone Pain + Tenderness + Proximal Myopathy

A

Osteomalacia

67
Q

Which drug can be used for Raynauds?

A

Nifedipine

68
Q

What should be done before starting biologics for RA?

A

Chest XRay

69
Q

Complement levels during active SLE Flare:

A

Low

70
Q

Which ANCA is associated with UC?

A

pANCA