Rheumatology antibodies Flashcards
1
Q
ank spond
A
no antibody
‘ANCA associated maybe’
2
Q
ank spond HLA
A
B27
3
Q
antiphospholipid antibody
A
cariolipin and lupus anticoagulant
4
Q
behctes HLA
A
B51
5
Q
dermatomyositis
- sensitive
- specific
A
80% ANA
30% anti-tRNA (anti-Mi most specific. also antiJo)
6
Q
drug induced lupus
- sensitive
- specific
- shitty 5% ones?
A
100% ANA
90% anti-histone
(ro and smith are 5%)
7
Q
PAN
A
pANCA
8
Q
RA
- sensitive
- specific
- HLA
A
sensitive = 70% RF and CCP
specific = CCP
HLADR4/DR1
9
Q
sjogrens
- sensitive
- specific
- other shitty one
A
sensitive = RF (100%)
specific = anti-Ro (70% - so is ANA)
shitty 30% = La
10
Q
which antibody causes neonatal heart block
A
anti-Ro
don’t (cant) cry about it
11
Q
SLE
- sensitive
- specific
- disease monitirng
- other shitty ones
A
sensitive = ANA
specific = smith
diease mnitirng = dsDNA
other shitties = ro, la, RF
12
Q
systemic sclerosis
- sensitive
- specif (liminted)
- specific (diffuse)
A
ANA 90%
centromere
scl-70
