Rheumatology

Question 1

ankylosing spondylitis Tx

Answer 1

1st line : NSAIDs
2nd line : Infliximab, etanercept, adalimumab, golimumab

**DMARDS are not indicated when there is axial involvement in rheumatic diseases.

Question 2

seronegative spondyloarthropathy

which diseases?

Answer 2

ankylosing spondylitis
reactive arthritis
psoriatic arthritis
inflammatory bowel disease

Question 3

the most common deficiency in patients with celiac disease

Answer 3

iron deficiency

Question 4

Tx for rheumatoid nodules?

Answer 4

intralesional steroid injection

• only treated for cosmetic or functional reasons. DMARDs actually make them worse.

Question 5

hemoptysis, hematuria,
recurrent rhinitis and sinusitis
+c-ANCA (antineutrophil cytoplasmic antibody)
+anti PR3

Answer 5

granulomatosis with polyangiitis
(Wegener’s granulomatosis)

Tx with steroid, methotrexate

Question 6

asthma, paranasal sinusitis, rapidly progressing GN
eosinophilia
+ANCA

Answer 6

Churg-Strauss syndrome

Tx with steroid

Question 7

acute GN, hemoptysis

+anti GBM (glomerular basement membrane)

Answer 7

Goodpasture’s syndrome

Tx with steroid, cyclophosphamide