Infection Flashcards
meningitis most common pathogen and empirical treatment? (for different age groups)
- 0-2 months (Group B streptococcus, E.Coli) : benzylpenicillin + cefotaxime
- >2months (N. Meningitidis, HiB, S pneumoniae) : ceftriaxone or cefotaxime, vancomycin if Gram positive
meningitis prophylaxis?
children, pregnant : Ceftriaxone
other adults : ciprofoxacin or rifampin
(rifampin contraindicated in severe liver disease, alcoholism)
a child with itching scalp, patchy loss of hair, scaling.
Dx and Tx?
Dx : Tinea capitis
Tx : PO antifungals (griseofulvin or terbinafine)
spontaneous baterial peritonitis
Dx, most common pathogen and Tx ?
ascitic fluid PMN > 250uL,
confirmed by culture
most commonly E.coli and other gut bacterial
initial Tx cefotaxime 2g IV 8 hourly
measles
how many days of school exclusion?
4 days from the onset of the rash
Tetanus vaccine schedule
- DTPa 5 doses : 2, 4, 6 and 18 months, and 4 yrs old.
- dTPa (reduced antigen) booster :
- at 11-13 yrs
- > 50 yrs old if last dose was more than 10 yrs ago
- >65 yrs old if last dose was more than 10 yrs ago
an adult never been vaccinated against tetanus in the past. what to give?
- dT 3 doses with 4 weeks intervals (1st dose should be dTPa. all three can be dTPa)
- booster (dT or dTPa at 10 and 20 yrs after the primary doses)
18 months
high fever for 3 days
fever suddley subsides and maculopapular rash on trunk
no rash on face or limb
Dx?

roseola infantum
caused by HHV-6 or 7
severe endometritis?
what pathogens to cover?
which Abx?
what if she has a history of anaphylaxis to penicillin?
gonorrhea, chlamydia
ceftriaxone, azithromycin + metronidazole.
gentamicin, azithromycin + metronidazole
adult community acquired pneumonia.
empirical Abx?
Is it mild, moderate,severe?
- Confusion : new onset
- O pO2 <60mm or O2 sat <90
- RR >30
- BP sys <90 or diast < 60
none: mild, 1 : moderate, 2 or more: severe
mild :
- amoxicillin 1g PO 8 hourly,
- review in 48 hours.
- (if cannot review in 48 hours, consider using doxycycline instead)
- imporved –> 5 days,
- slow improvement, 7 days.
moderate : admission
- benzylpenicillin + doxycycline OR clarithromycin
Severe : ICU
- benzylpenicillin +gentamicine + clarithromycin
the most common cause of gastroenteritis in adults and older children in australia?
in young children?
adults and older children : norovirus
youger children : rotavirus
thumb sign on lateral neck xray
Dx
m/c pathogen
Tx
- epiglotittis
- Past : H influenzae type B (not anymore due to the vaccine)
- Current : Group A beta hemolytic streptoccocus
- don’t delay airway protection because od Xray
cellulitis Abx?
IV flucoloxacillin
difloxacillin
hepatic hydatid cyst
which pathogen?
hosts?
how to eradicate?
human treatment?
- pathogen : echinococcus
- main host : dogs. intermediate host : sheep. accodental host : humans
- eradication? :vaccination of lambs, deworming of dogs
- Percutaneous drainage with albendazole therapy
exposure to measles.
Management?
1) Hx of vaccination (+)
2) vaccination history unsure
3) pregnant, immunecompromised, not sure of vaccination
1) Hx of vaccination (+) : reassure
2) vaccination history unsure : MMR vaccine now and 4 weeks later
3) pregnant, immunecompromised, not sure of vaccination : natural human immunoglobulin (NHIG)
three strategies to reduce perinatal HIV transmission?
- use of zidobudine for the mom and baby
- elective C-sec
- no breastfeeding
prophylactic antibiotics for HIV patients with low CD4 count?
what species to cover?
need to cover,
- < 200: toxoplasmosis
- < 100 : Pneumocystis jiroveci
- < 50 : MAC
use
- trimethoprim-sulfamethoxazole : for toxo and PCJ
- azithromycin : for MAC
diabetic foot ulcer anti?
mild infection : PO amoxicillin-clavulanate
deep or widespread infections, osteomyelitis : piperacillin-tazobactam, ticarcillin-clavulanate, meropenem, ertapenem, carbapenem,
moxi or ciprofloxacin + metronidazole
3rd cephalosporin + metronidazole
a man travelled to Thailand recently
presented with
fever, joint pain, retro-orbital pain, rash all over body,
no LAP,
leukopenia, thrombocytopenia. elevated AST
dengue fever
diffuse patchy infiltrates on x ray
suspected atypical pneumonia
What is the most common pathgen in each age group?
children < 2 yrs
school aged children
children < 2 yrs : viral pneumonia
school aged children : mycoplasma pneumoniae
scabies Tx
permethrin 5% cream
adult, recurrent sinusitis, failed with amoxacillin, trimethoprim/sulphamethoxazole.
Tx?
a fluoroquinolone 14-21 days
roundworm infection Tx?
(Ascarid lumbricoid infection)
Pyrantel
the most common pathogen for hospiral-acquired pneumonia
S. aureus
P. aeruginosa
child with suspected pneumonia.
Tx?
out patient : amoxacillin 3-5 days
inpatient, not severe : amoxacillin. (if unable to take orally, consider benzylpenicillin IV)
inpatient, sever (ICU) : ceftriaxone + azithromycin
Malaria prophylaxis with… ?
in Thai/Myanmar/Cambodia
in Central America
in South America or Africa
Thai/Myanmar/Cambodia : doxycycline, atovaquone-proguanil
Central America : chloroquine (chloroquine worsens psoriasis)
South America or Africa : Mefloquine (mefloquine can cause panic attacks, paranoia)
vaccines that contain egg proteins?
Influenza
yellow fever
Q fever
typhoid or paratyphoid fevers (enteric fevers)
salmonella from India
Tx?
azithromycin or ceftriaxone
India
use ciprofloxacin only if stool culture or blood cultures confirm the sensitivity.
Rheumatic fever
the revised Jones criteria
- 2 Major
- 1 major + 2 minor + recent confirmed GAS infection (anti streprolysyn Ab, rapid antigen test for strep A , throuat culture)
Major
- carditis
- polyarthritis
- chorea
- erythema marginatum
- subcutaneous nodules
Minor
Clinical
arthralgia
fever
laboratory
elevated ESR/CRP
1st degree AV block
the most common pathogen for pneumonia in patients with cystic fibrosis
under 5 years old ?
10 years and older?
- under 5 years old : S. aureus
- 10 years and older : Pseudomonas aeruginosa
sore throat.
when to give antibiotics?
streptococcal score
- no cough
- fever > 38
- cervical LN
- tonsillar exudates
- age 3-14
0-1: supportive care
2-3 : culture, or RADT–> Abx if positive
>4 : treat with amoxicillin