Rheumatology Flashcards

1
Q

RA first-line DMARD?

A

Methotrexate

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2
Q

What can you not prescribe methotrexate with?

A

Trimethoprim!!

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3
Q

First line imaging for RA?

A

MRI scan for soft tissue damage. XR look for erosive damage

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4
Q

Biological + targeted DMARD for RA?

A

TNF alpha blocker. Jakinib is targeted

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5
Q

Examination findings in ankylosing spondyloarthritis?

A

Reduced Schoeber’s test
Reduced lateral flexion
Spinal tenderness

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6
Q

First line imaging ankylosing spondyloarthritis?

A

MRI

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7
Q

Blood tests for ankylosing spondyloarthritis?

A

HLA-B27, CRP

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8
Q

Which drugs are used in ankylosing spondyloarthritis?

A

Analgesics, NSAIDs, TNF alpha blocker
NOT STEROID PREPARATIONS OR CONVENTIONAL DMARDs

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9
Q

Treatment of ankylosing spondyloarthritis

A

Analgesics, NSAIDs, TNF alpha blocker
MDT approach: support nurses, physio, relevant charities/support groups

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10
Q

Describe psoriatic arthritis?

A

Nail changes, small and larger joints.
Imaging

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11
Q

Treatments for psoriatic arthritis?

A

Can be steroids with care, methotrexate, TNF alpha

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12
Q

Seronegative spondylo-arthropathies?

A

Ankylosing spondylitis, reactive arthritis, psoriatic arthritis, enteropathic arthritis

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13
Q

Ix of reactive arthritis?

A

CRP, HLA-B27, ASOT, STI screen, US/MRI

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14
Q

Treatment for reactive arthritis?

A

Steroid injections, methotrexate, sulfasalazine
NOT BIOLOGICAL THERAPIES

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15
Q

Features of spondyloarthritis

A

Sacroileitis, iritis, dactylitis

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16
Q

Reactive arthritis: causative organisms?

A

Chlamydia, GU infection, shigella, salmonella, yersinia, E.coli, campylobacter

17
Q

Osteoporosis risk factors?

A

Low vitamin D, type of fracture, menopause, HRT, autoimmune diseases, smoking/alcohol, sun exposure, DEXA scan

18
Q

T vs Z score?

A

T is to healthy 25 y/o.
Z score is age-matched individual

19
Q
A