Infectious disease Flashcards
What % of hep B goes chronic?
5-10%
What % of hep C goes chronic?
60-80%
Hep C associations?
HCC, thalassaemia
Painless ulcer + painless lymphadenopathy?
Syphilis
Painless ulcer (perianal) + painful lymphadenopathy?
LGV
small painless pustule ulcer painful lymphadenopathy proctocolitis (PR bleeding, discharge, ulceration around the peri-anal area
Chlamydia
o Painful ulcer + painful lymphadenopathy
chancroid
Treatment for falciparum malaria?
Mild = oral malarone
Severe = IV Artesunate
- Hypoglycaemia mx
- Hydrate cautiously
- Monitor parasitaemia
Non-falciparum malaria tx?
Chloroquine
Ix for malaria?
3 thick and thin blood films (thick = parasite; thin = species, parasitaemia)
Malaria rapid antigen detection tests (plasmodial HRP-II, parasite LDH)
Features of typhoid?
Anorexia, Rose spots, bradycardia, splenomegaly,
Mx of typhoid?
1st line = IV ceftriaxone OR IV cefotaxime
2nd line = PO azithromycin
S/S of dengue fever?
o Signs & symptoms (low WCC, low plts, low Hb):
Primary infection:
* Headache (retro-orbital)
* Fine erythematous sunburn-like rash (50%)
* High fever and myalgia
Other = hepatomegaly, abdominal distension
Severe = low WCC, low platelets, haemorrhage
Dengue haemorrhagic fever (secondary infection):
* Previously infected child subsequent infection (different strain) severe capillary leak, hypotension, haemorrhagic manifestations fluid resuscitation usually helps a lot
* Due to partially effective host immune response augmenting the severity of the infection
Tx for lyme disease?
Doxycycline
S/s and tx of leptospirosis?
Conjunctival haemorrhages, jaundice, canoeing, uveitis
Doxycycline