Infectious disease Flashcards

1
Q

What % of hep B goes chronic?

A

5-10%

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2
Q

What % of hep C goes chronic?

A

60-80%

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3
Q

Hep C associations?

A

HCC, thalassaemia

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4
Q

Painless ulcer + painless lymphadenopathy?

A

Syphilis

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5
Q

Painless ulcer (perianal) + painful lymphadenopathy?

A

LGV

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6
Q

small painless pustule  ulcer  painful lymphadenopathy  proctocolitis (PR bleeding, discharge, ulceration around the peri-anal area

A

Chlamydia

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7
Q

o Painful ulcer + painful lymphadenopathy

A

chancroid

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8
Q

Treatment for falciparum malaria?

A

Mild = oral malarone

Severe = IV Artesunate
- Hypoglycaemia mx
- Hydrate cautiously
- Monitor parasitaemia

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9
Q

Non-falciparum malaria tx?

A

Chloroquine

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10
Q

Ix for malaria?

A

 3 thick and thin blood films (thick = parasite; thin = species, parasitaemia)
 Malaria rapid antigen detection tests (plasmodial HRP-II, parasite LDH)

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11
Q

Features of typhoid?

A

Anorexia, Rose spots, bradycardia, splenomegaly,

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12
Q

Mx of typhoid?

A

 1st line = IV ceftriaxone OR IV cefotaxime
 2nd line = PO azithromycin

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13
Q

S/S of dengue fever?

A

o Signs & symptoms (low WCC, low plts, low Hb):
 Primary infection:
* Headache (retro-orbital)
* Fine erythematous sunburn-like rash (50%)
* High fever and myalgia
 Other = hepatomegaly, abdominal distension
 Severe = low WCC, low platelets, haemorrhage

 Dengue haemorrhagic fever (secondary infection):
* Previously infected child  subsequent infection (different strain)  severe capillary leak, hypotension, haemorrhagic manifestations  fluid resuscitation usually helps a lot
* Due to partially effective host immune response augmenting the severity of the infection

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14
Q

Tx for lyme disease?

A

Doxycycline

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15
Q

S/s and tx of leptospirosis?

A

Conjunctival haemorrhages, jaundice, canoeing, uveitis
Doxycycline

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16
Q

Human Plague bacteria?

A

Yersinia pestis

17
Q

AIDs-defining diseases

A

PCP, Kaposi’s sarcoma, MAC, oesophageal candidiasis

18
Q

HIV investigations?

A
  • 1st: ELISA
  • 2nd: Western Blot Assay confirmatory testing
19
Q
A