Palliative Care Flashcards
o Starting doses for oromorph?
2.5-5mg, 4-hourly
if pain not 90% relieved, how much should the dose be increased by?
o Increase by 1/3rd (30-50%)
o Breakthrough doses of morphine should be what?
= 1/6th of total morphine in 24 hours
Bony metastasis pain:
1st: Analgesia
2nd: Bisphosphonates
3rd: Radiotherapy
- Immediate release morphine formualations: (IR; ≤4 hours):
o Oromorph (liquid)
o Sevredol (tablet)
o Morphine injection
- Modified release morphine (MR):
o MST / zomorph (BD)
o MXL (OD)
Metoclopramide - avoid in which patients?
- Avoid in Parkinson’s (DA antagonist) – use domperidone (does not cross BBB)
- Avoid in young women (risk of dyskinesia i.e. acute dystonia)
Which anti-emetic to prescribe in fluid retention?
Metoclopramide, avoid cyclizine
Vestibular N&V drug choice?
Cyclizine
Raised ICP N&V drug choice?
Cyclizine (± dexamethasone)
Chemical N&V drug choice?
Ondansetron, haloperidol, levomepromazine
Which drug for chemotherapy nausea?
Ondansetron
Gastric stasis N&V drug choice?
Metoclopramide (CI: BO), domperidone
Constipation, oral candidiasis N&V drug choice?
Cyclizine, levomepromazine
Anxiety, pain, fear, anticipatory nausea N&V drug choice?
BDZ (lorazepam), cyclizine
2nd line Mx for agitation/confusion?
o 2nd line: chlorpromazine, levomepromazine
Terminal restlessness treatment?
Midazolam (PRN SC injections or SC infusion by syringe driver)