Rheumatology Flashcards
Antiphospholipid Sx: bloods
Prolonged APTT and low platelets
PO bisphosphonates prior to starting
Correct hypocalcaemia & vitamin d
Osteoporosis
Ca: normal
PO4: normal
ALP: normal
PTH: normal
Osteomalacia
Ca: decreased
PO4: decreased
ALP: Increased
PTH: Increased
CKD
Ca: decreased
PO4: increased
ALP: increased
PTH: increased
Paget’s
Ca: normal
PO4: normal
ALP: increased
PTH: normal
Osteosarcoma
Most frequently in long bones prior to growth plate fusion
Lupus: antibodies
ANA +ve
Anti-histone
Meralgia paraesthetica
Compression of lateral cutaneous nerve
Hypersensitivity reactions: I
Anaphylaxis
Hypersensitivity reactions: II
Cell bound
Autoimmune
Hypersensitivity reactions: III
Immune complex
SLE, post strep GN
Hypersensitivity reactions: IV
delayed hypersensitivity
Osteomalacia: features
Bone pain
Bone tenderness
Waddling gait
OP: >75 years
Fragility # and over 75 start bisphosphonates without DEXA