Rheumatology Flashcards

1
Q

Antiphospholipid Sx: bloods

A

Prolonged APTT and low platelets

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2
Q

PO bisphosphonates prior to starting

A

Correct hypocalcaemia & vitamin d

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3
Q

Osteoporosis

A

Ca: normal
PO4: normal
ALP: normal
PTH: normal

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4
Q

Osteomalacia

A

Ca: decreased
PO4: decreased
ALP: Increased
PTH: Increased

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5
Q

CKD

A

Ca: decreased
PO4: increased
ALP: increased
PTH: increased

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6
Q

Paget’s

A

Ca: normal
PO4: normal
ALP: increased
PTH: normal

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7
Q

Osteosarcoma

A

Most frequently in long bones prior to growth plate fusion

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8
Q

Lupus: antibodies

A

ANA +ve
Anti-histone

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9
Q

Meralgia paraesthetica

A

Compression of lateral cutaneous nerve

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10
Q

Hypersensitivity reactions: I

A

Anaphylaxis

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11
Q

Hypersensitivity reactions: II

A

Cell bound
Autoimmune

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12
Q

Hypersensitivity reactions: III

A

Immune complex
SLE, post strep GN

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13
Q

Hypersensitivity reactions: IV

A

delayed hypersensitivity

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14
Q

Osteomalacia: features

A

Bone pain
Bone tenderness
Waddling gait

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15
Q

OP: >75 years

A

Fragility # and over 75 start bisphosphonates without DEXA

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16
Q

DEXA: >-2.5

A

Confirmed OP

17
Q

Psoriatic arthropathy: cf

A

Symmetrical polyarthritis
Asymmetrical oligoarthritic
DIP disease

18
Q

MTX: SE

A

Myelosuppression
Liver cirrhosis
Pneumonitis

19
Q

Sulfasalazine: SE

A

Rashes
Oligospermia
Heinz body anaemia
ILD

20
Q

RA: Poor prognosis features

A

Rh factor +ve
Anti-CCP ABs
Poor functional status
Early erosions
Extra articular features
HLA DR4
Insidious onset

21
Q

RA: X ray changes

A

Loss of joint space
Juxta-articular OP
Soft tissue swelling
Periarticular erosions
Subluxation

22
Q

Systemic sclerosis: Antibodies

A

ANA +ve in 90%
RF +ve in 30%

23
Q

Bloods before azathioprine

A

TPMT

24
Q

Sjogren’s antibodies

A

Anti-Ro