Rheumatology

Question 1

Two meds that inhibit Xanthine Oxidase and used to treat gout?

Answer 1

Allopurinol and febuxostat

Question 2

Meds to treat gout

Answer 2

Allopurinol, febuxostat, probenecid, pegloticase

Question 3

Gout med you cannot use in renal dz?

Answer 3

Probenecid

Question 4

Uric acid goal

Answer 4

<0.6mg/dL

Question 5

Which gout med do you use in refractory treatment

Answer 5

Pegloticase

Question 6

What should you test for before starting pegloticase?

Answer 6

G6PD deficiency

Question 7

How does probenecid work?

Answer 7

Blocks Transporter and increases urine excretion

Question 8

Ddx for acute monoarticular arthritis

Answer 8

Acute monoarticular arthritis is due to infectious arthritis, hemarthrosis, or acute crystalline arthritis; joint fluid analysis is necessary to make the correct diagnosis.

Question 9

Association between gouty arthritis and psoriasis

Answer 9

It is thought that the rapid turnover of skin cells in patients with psoriasis drives protein metabolism and increases serum urate levels

Question 10

Adjunct to high dose steroids in ANCA vasculitis

Answer 10

Rituximab or cyclophosphamide