Oncology

Question 1

In breast CA- should you biospy the primary site or metastatic site

Answer 1

Metastatic. Breast cancer can undergo subtype switch between the primary disease and metastatic disease, and biopsying the metastatic site allows treatment to be tailored to the metastatic disease subtype.

Question 2

Treatment for respectable non small cell lung cancers

Answer 2

Cisplatin based chemotherapy only (radiation when non resectable)

Question 3

Treatment for EGFR mutations in cancer

Answer 3

Erlotinib

Question 4

Treatment for ROS1 or ALK mutations in cancer

Answer 4

Alectinib

Question 5

AML patients who complete remission should receive

Answer 5

Stem cell transplant. Patients with AML who initially achieve complete remission will relapse unless additional postremission therapy is provided.

Question 6

Treatment for anal cancer

Answer 6

Anal cancer is often curable with combined irradiation and chemotherapy; surgery is typically not indicated.