Rheumatology Flashcards

1
Q

What antibody is investigated in Scleroderma and is it diffuse or limited?

A

SCL-70 and Diffuse

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2
Q

What symptoms are present in Limited CREST and what antibody is being tested?

A

Calcinosis, raynaud’s, esophygeal dysmotility, sclerodactyly, telangiectasias. Centromere.

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3
Q

What is the diagnostic investigation for Rheumatoid arthritis?

A

Anti-CCP

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4
Q

What is Sjorgen’s disease? and what antibodies are tested?

A

SICCA - Dry eyes and mouth. Anti-SSA, Anti-SSB and RO/LA

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5
Q

In what condition do you find Livedo reticularis?

A

Polyarteritis Nodosa - Inflammation of the arteries, can lead to tissue necrosis.

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6
Q

What is the diagnostic test for Temporal Arteritis and it’s treatment?

A

Temporal Biopsy & Steroid

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7
Q

Intermittent 1 or 2 fevers a day with joint pain and stiffness in a child less that 16 years of age is known as?

A

Juvenile Rheumatoid Arthritis

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8
Q

Which rheumatoid condition causes muscle pain?

A

Polymyalgia Rheumatica

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9
Q

What condition causes Muscle Weakness and what how is it a) investigated? b) diagnosed?

A

Polymyoistitis - Electromyography and Muscle Biopsy

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10
Q

What is the difference between Reiter’s Syndrome and Septic Arthritis?

A

Reiter’s syndrome - Reactive arthritis - delayed response, usually three weeks after an infection in the body.
Septic Arthritis - Inflammatory response to an infection in a single joint.

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11
Q

What crystals are seen in Gout vs Pseudogout

A

Negative birefringent crystals (Rod shaped and needle) vs Positive birefringent crystals (rod-shaped with blunt ends).

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12
Q

If C3 and C4 are low, is that indicative of a controlled SLE?

A

NO - C3 and C4 are part of the immune system complement system. If it is low the disease is highly active.

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13
Q

What 3 conditions is someone susceptible to if they have the HLA-B27 gene?

A

Ankylosing spondylitis, Crohns, Reiter’s Syndrome

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14
Q

What condition is associated with 12 trigger points?

A

Fibromyalgia

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