Rheumatoid Arthritis, Gout and Avascular Necrosis Flashcards

1
Q

What causes rheumatoid arthritis?

A

it has an unknown cause but has clear links with the immune system and a potential genetic link

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2
Q

What is the clinical picture of rheumatoid arthritis?

A

severe pain
swelling
deformity

commonly small joints of the hands and feet affected with symmetrical pattern

large joints are infrequent but also no symmetry

More common in women

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3
Q

What do patients with rheumatoid arthritis first notice symptom wise?

A

stiffness - particularly in the morning and then improves throughout the day

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4
Q

What is the role of surgery?

A

ensure comfort - RA is a primarily medically treated disease

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5
Q

What happens in soft tissue surgery for RA?

A

tendon sheaths and tendons can be damaged, and this can be halted sometimes by synovectomy. Occasionally tendons actually rupture and a repair is needed

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6
Q

What is an excision arthroplasty?

A

Some of the joint is removed which helps decrease pain but limits functionality

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7
Q

What is avascular necrosis?

A

Bone tissue death through loss of blood supply

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8
Q

What can cause avascular necrosis?

A

Trauma

unknown cause

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9
Q

What areas are particularly at risk to AVN?

A

femoral head
scaphoid
proximal talus

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10
Q

What is Caisson’s disease?

A

AVN in deep sea divers

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11
Q

What factors can cause AVN in strange circumstances?

A

chronic alcohol abuse
steroids
Caisson’s

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12
Q

How is AVN diagnosed?

A

difficult on x-ray until later when the bone becomes dense
sometimes it can revascularise normally but with some deformity
surgical blood supply restoration is not possible just now

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13
Q

How is AVN managed?

A

non-specific
rest
joint replacement salvage is all that can be done

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14
Q

What is gout?

A

Gout is a painful joint condition caused by urate crystal deposition into the joint typically in dehydration or after chemotherapy

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15
Q

what can cause gout?

A

dehydration
diuretics
chemotherapy

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16
Q

How does gout present?

A

hot, painful, swollen joint.

typically the big toe and also the knee.

17
Q

What condition is important to exclude in suspected gout?

A

septic arthritis

18
Q

How is a gout diagnosis made?

A

Testing for urate in the blood

Extracting joint synovial fluid and viewing under polarised light. - negatively bifringent

19
Q

How is gout treated?

A

NSAIDs
colchicine
Allopurinol long term

20
Q

What is psuedogout

A

less acute presentation of a hot swollen tender joint caused by pyrophosphate crystal deposition into the joint

21
Q

What happens to joints in chronic pseudogout?

A

degeneration and calcification (menisci)