Rheumatoid Arthritis Flashcards
1
Q
is an autoimmune disease that primarily attacks the joints, leading to inflammation, pain, and eventual joint damage
A
Rheumatoid Arthritis
2
Q
What is the gene associated with RA?
A
HLA-DRB1
3
Q
What are the exogenous cause of RA?
A
Smoking
Infections
Hormonal factors
4
Q
What are the notable MHC molecules of RA?
A
HLA-DRB1
HLA-DQ
5
Q
What is the target organ of RA?
A
Synovial membrane
6
Q
What are the effects of RA on tissues?
A
Synovial hyperplasia
Bone erosion
Cartilage degradation
Systemic Effects
7
Q
What are the signs and symptoms of RA?
A
Fatigue
Anorexia
Weakness
Generalized aching
Stiffness
Joint paint
Swelling
8
Q
What are the laboratory testing for diagnosis under RF?
A
Erythrocyte Sedimentation Rate and CRP
