Rheumatoid Arthritis

Question 1

Q. If RA ptn is allergic to Co-Trimoxazole ( trimethropine+ sulfamethoxazole) then what drug is contraindicated for this ptn?

Answer 1

Sulphasalazine

Question 2

Q. In treating ptn for RA who has glucose-6 phosphate dehydrogenase deficiency. What drug is contraindicated?

Answer 2

Hydroxychloroquine will cause hemolysis in these ptn

Question 3

Q. What’s the earliest radiographic manifestation of RA?

Answer 3

Juxta-articular demeniralizarion

Question 4

N. Anti CCP is very specific for….?

Answer 4

RA

Question 5

N. What’s the predominant lymphocytes in RA inflammation?

Answer 5

T- lymphocytes

Question 6

N. ………..deviation of the wrist with……..deviation of the digits

Answer 6

Radial = wrist / ulnar = digits

Question 7

N- Boutonnières deformity & Swan-neck deformity are seen in?

Answer 7

RA

Question 8

N. ( RA + splenomegaly + neutropenia) name the syndrome?

Answer 8

Felty syndrome

Question 9

N. ( RA + pneumoconiosis) m

Name the syndrome?

Answer 9

Caplan syndrome

Question 10

N. Name one side effect of hydroxychloroquine ?

Answer 10

Retinopathy

Question 11

N. Name 4 side effect of methotrexate?

Answer 11

Hepatitis, hepatic fibrosis, pneumonitis, flare the rheumatoid nodule

Question 12

N. HLA…… is ass. With RA

Answer 12

HLA DR4

Question 13

N. Name an eye complication of RA?

Answer 13

Keratoconjunctivites sicca ( while retinopathy is a complication of RA treatment by hydroxychloroquine )

Question 14

N. RF is an .… antibodies against fc IgG .

Answer 14

IgM

Question 15

N. Name the antibodies ass. With RA? 2

Answer 15

Anti-CCP / RF