Mix Flashcards
Q. What’s the maximum dosage of acetaminophen for ptn who weighs 70 Kg in 24 hours?
4000mg
A. Name the 4 spondyloarthropathies that are ass. With Hla B27 ?
Ankylosing spondylitis/ reactive arthritis/ psoriatic arthritis/ Reiter’s syndrome
Q. Is tumor necrosis factor @ is pro-inflammatory cytokines or anti-inflammatory cytokines?
TNF @ Is pro inflammatory / the anti-inflammatory cytokines are IL4, IL10
A. What’s the medication used to inhibit TNF@ as in treatment of RA?
Infleximab
Q……….. syndrome has a strong ass. With HLA B27?
Reiter’s syndrome
A. Anticentrometric Antibody is a marker for……..?
CREST ( form of scleroderma )
N- Polyarticular symmetric involvement is seen in…….? 4
- Polyarticular symmetric involvement is seen in:
1. Rheumatoid arthritis
2. SLE
3. Parvovirus B19
4. Hepatitis B
N- Monoarticular arthritis …..?
- Osteoarthritis
- Crystal-induced arthritis ( gout, pseudogout)
- Septic arthritis ( gonococcus)
- Trauma
- Hemarthrosis
N- Migratory arthropathy seen in ……?
- Rheumatic fever
- Disseminated gonococcal infection
- Lyme disease
N- Oligoarticular asymmetric arthritis seen in……?
- Ankylosing spondylitis
2. Osteoarthritis involving small joint of upper extremities and rarely as a presentation of polyarticular gout
N. Anti centromere ANA is found in…..?
CREST
N. Anti sm ANA is found in?
SLE 30%
N. Anti histone ANA is found in….?
Drug induced lupus 95%
N. Anti RO ( SSA ) is found in…..?
Neonatal lupus & Sjögren
N. Anti LA ( SSB ) is found in……?
Sjögren
N. Anti RNP ANA is seen in ……?
Mixed connective tissue disease
N. Nuclear pattern of ANA is seen in……? While peripheral pattern is found in….?
Systemic sclerosis / peripheral = SLE
N. Anti ds DNA is found in?
SLE only 60%; indicator of disease activity of lupus nephritis
N- ANCAs are antibodies directed against certain proteins in the ………..of neutrophils
- Type c ( ANCA ) Is seen in >90% of …….. ………. ptn
- There is also type p (ANCA ) but not specific
Cytoplasm / Wegener granulomatosis
N. What’s Antiphospholipid antibody syndrome
( lupus anticoagulant or anticardiolipin antibodies ) ?? And what’s the S&S ?
- Is a hypercoaguble state ass. With group of antibodies directed against phospholipids or cardiolipins
- ⬆️PTT
- False positive RPR OR VDRL
- Present with spontaneous abortion in healthy woman ( usually in two first-trimester)
- Thromboembolism, PE, DVT
N. In what disease you see bulls eye lesion?
Lyme disease
N. Biceps tendinopathy + subacromial bursitis + glenohumeral synovitis are features of …..?
Polymyalgia rheumatica
N. What’s the DD of posterior heel pain?
Calcaneal stress fracture / retrocalcaneal bursitis / Enthisitis from reactive arthritis / Achilles tendinopathy
N. Name the autoimmune arthritis? 3
Connective tissue disease ( RA, SLE, Sjögren, SS, inflammatory myositis ) / seronegative arthritis/ vasculitis
N. Name the diseases in spondyloarthrothides ? 4
IBD-related arthritis/ ankylosing spondylitis/ reactive arthritis/ psoriatic arthritis
Name the diseases ass. With U1 RNP antibody?
Mixed connective tissue disease