Mix

Question 1

Q. What’s the maximum dosage of acetaminophen for ptn who weighs 70 Kg in 24 hours?

Answer 1

4000mg

Question 2

A. Name the 4 spondyloarthropathies that are ass. With Hla B27 ?

Answer 2

Ankylosing spondylitis/ reactive arthritis/ psoriatic arthritis/ Reiter’s syndrome

Question 3

Q. Is tumor necrosis factor @ is pro-inflammatory cytokines or anti-inflammatory cytokines?

Answer 3

TNF @ Is pro inflammatory / the anti-inflammatory cytokines are IL4, IL10

Question 4

A. What’s the medication used to inhibit TNF@ as in treatment of RA?

Answer 4

Infleximab

Question 5

Q……….. syndrome has a strong ass. With HLA B27?

Answer 5

Reiter’s syndrome

Question 6

A. Anticentrometric Antibody is a marker for……..?

Answer 6

CREST ( form of scleroderma )

Question 7

N- Polyarticular symmetric involvement is seen in…….? 4

Answer 7

• Polyarticular symmetric involvement is seen in:
  1. Rheumatoid arthritis
  2. SLE
  3. Parvovirus B19
  4. Hepatitis B

Question 8

N- Monoarticular arthritis …..?

Answer 8

1. Osteoarthritis
2. Crystal-induced arthritis ( gout, pseudogout)
3. Septic arthritis ( gonococcus)
4. Trauma
5. Hemarthrosis

Question 9

N- Migratory arthropathy seen in ……?

Answer 9

1. Rheumatic fever
2. Disseminated gonococcal infection
3. Lyme disease

Question 10

N- Oligoarticular asymmetric arthritis seen in……?

Answer 10

1. Ankylosing spondylitis

2. Osteoarthritis involving small joint of upper extremities and rarely as a presentation of polyarticular gout

Question 11

N. Anti centromere ANA is found in…..?

Answer 11

CREST

Question 12

N. Anti sm ANA is found in?

Answer 12

SLE 30%

Question 13

N. Anti histone ANA is found in….?

Answer 13

Drug induced lupus 95%

Question 14

N. Anti RO ( SSA ) is found in…..?

Answer 14

Neonatal lupus & Sjögren

Question 15

N. Anti LA ( SSB ) is found in……?

Answer 15

Sjögren

Question 16

N. Anti RNP ANA is seen in ……?

Answer 16

Mixed connective tissue disease

Question 17

N. Nuclear pattern of ANA is seen in……? While peripheral pattern is found in….?

Answer 17

Systemic sclerosis / peripheral = SLE

Question 18

N. Anti ds DNA is found in?

Answer 18

SLE only 60%; indicator of disease activity of lupus nephritis

Question 19

N- ANCAs are antibodies directed against certain proteins in the ………..of neutrophils

• Type c ( ANCA ) Is seen in >90% of …….. ………. ptn
• There is also type p (ANCA ) but not specific

Answer 19

Cytoplasm / Wegener granulomatosis

Question 20

N. What’s Antiphospholipid antibody syndrome

( lupus anticoagulant or anticardiolipin antibodies ) ?? And what’s the S&S ?

Answer 20

• Is a hypercoaguble state ass. With group of antibodies directed against phospholipids or cardiolipins
• ⬆️PTT
• False positive RPR OR VDRL
• Present with spontaneous abortion in healthy woman ( usually in two first-trimester)
• Thromboembolism, PE, DVT

Question 21

N. In what disease you see bulls eye lesion?

Answer 21

Lyme disease

Question 22

N. Biceps tendinopathy + subacromial bursitis + glenohumeral synovitis are features of …..?

Answer 22

Polymyalgia rheumatica

Question 23

N. What’s the DD of posterior heel pain?

Answer 23

Calcaneal stress fracture / retrocalcaneal bursitis / Enthisitis from reactive arthritis / Achilles tendinopathy

Question 24

N. Name the autoimmune arthritis? 3

Answer 24

Connective tissue disease ( RA, SLE, Sjögren, SS, inflammatory myositis ) / seronegative arthritis/ vasculitis

Question 25

N. Name the diseases in spondyloarthrothides ? 4

Answer 25

IBD-related arthritis/ ankylosing spondylitis/ reactive arthritis/ psoriatic arthritis

Question 26

Name the diseases ass. With U1 RNP antibody?

Answer 26

Mixed connective tissue disease