Gout & Pseudogout

Question 1

Q. In asymptotic ptn with slightly elevated serum urate, what’s the appropriate management ?

Answer 1

Just lifestyle change / low alcohol intake

Question 2

Q. What’s the mechanism of action of Allopurinol?

Answer 2

Inhibits xanthine oxidase irreversibly ( it’s the enzyme responsible for conversion of purine to uric acid )

Question 3

Q. If ptn has gout and he’s allergic to colchicine what’s the alternative medication?

Answer 3

Indomethacin

Question 4

N. After synovial fluid aspiration you willl find in gout, …….. shaped,…..ve birefringent. While pseudogout is …….shaped,…….ve birefringent.

Answer 4

Gout = needle shaped, negative birefringent/ pseudogout is rhomboid shaped and positive birefringent

Question 5

Small % of ptn with CPPD is associated with metabolic abnormalities (4H) what are they? ( pseudogout )

Answer 5

Hyperparathyroidism

Hemochromatosis

Hypophosphatemia

Hypomagnesemia

Question 6

Serum uric acid Has no value in acute cases and can be even low or normal and it can be high in ppl don’t have gout. True or false?

Answer 6

True

Question 7

Gout is ass. With male, binge drinking, …….shaped crystals while pseudogout ( calcium pyrophosphate deposition disease ) is ass. With ………. And ,………., it affects the wrist and …… and the crystal are ……shaped

Answer 7

Needle shaped, hemochromatosis & Hyperparathyroidism , knee, rhomboid shape