✅RHEUM/ORTHOPEDICS

Question 1

[Polymyalgia Rheumatica (PMR)] affects [____(demographic)]

________________

cp -2

Answer 1

[> 50 yo]

________________

1. [STIFF Neck, Shoulder, Hips]
2. INC ESR

Question 2

tx for [polymyalgia rheumatica (PMR)]

Answer 2

[prednisone low dose]

Question 3

What are the Main elements of SLE-15

Answer 3

RASH ORR PAINN

Question 4

Pagets disease of bone etx

Answer 4

Accelerated focal bone remodeling

⬆︎osteoclast activity f/b rapid and disorganized mosaic bone patterns from osteoBlast

tx = bisphosphonates

Question 5

Paget disease of bone cp -2

most common cause of asymptomatic ALP ⬆︎ in elderly

Answer 5

1. Bone/Joint pain +/- fx
2. Enlarging cranial bones –> ⬆︎hat size, HA, hearing loss from CN8 entrapment

• bx: disorganized mosaic pattern of lamellar bone*
• tx = bisphosphonates*

Question 6

Lab values for Paget disease of bone - 4

Answer 6

1. ⬆︎ALP
2. ⬆︎Urine Hydroxyproline (measures bone turnover)
3. NORMAL CALCIUM
4. NORMAL PHOSPHOROUS

bx: disorganized mosaic pattern of lamellar bone

Question 7

Tx for Paget disease of bone

Answer 7

Bisphosphonates

​bx: disorganized mosaic pattern of lamellar bone

Question 8

What is the most common cause of asymptomatic isolated ALP ⬆︎ in the elderly

Answer 8

Paget Disease of bone

• bx: disorganized mosaic pattern of lamellar bone*
• tx = bisphosphonates*

Question 9

Dx for Paget disease of bone - 2

Answer 9

Xrays showing osteolytic or mixed lytic-sclerotic lesions –> radionuclide bone scan for confirmation

​bx: disorganized mosaic pattern of lamellar bone

Question 10

_____ loss is a common complication of [Paget bone disease]

________________

tx? -2

Answer 10

hearing

________________

Bisphosphonates or Calcitonin

(treatment only slows progression)