Rhematology Flashcards

1
Q

Acute attack treatment for gout

A

1) NSAIDS- best initial therapy
2) corticosteroids
3) if can’t use NSAIDS or steroids then colchine

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2
Q

side effects of colchicine

A

diarrhea and bone marrow WBC supression ( neutropenia)

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3
Q

Drugs to avoid in gout

A

thiazides
niacin
aspirin

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4
Q

Best Bp med in gout

A

losartan

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5
Q

Pain worse when walking downhill, radiates into buttocks and thighs

A

lumbar spinal stenosis

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6
Q

anterior knee pain secondary to trauma worse just after starting walking after being seated for prolonged period. pain is particularly bad when going up and down stairs, normal x rays

A

pateollofemoral syndrome

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7
Q

Rhematoid arthritis
splenomegaly
neutropenia

A

Felty syndrome

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8
Q

Rheumatoid arthritis
pneumoconiosis
lung nodules

A

caplan syndrome

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9
Q

what are the adverse effects for methotrexate

A

liver toxicity
bone marrow suppression
pulmonary toxicity

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10
Q

you want to use TNF inhibitor such as infliximab, adalimumab, etanercept- what should you check before hand?

A

PPD- bc can cause reactivation of TB

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11
Q

Hydroxycholoroquine toxicity causes what?

A

retinal toxicity

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12
Q

presence of high spiking fevers in a young person with a salmon colored rash on chest and abdomen

A

juvenile rhematoid arthritis ( adult still disease)

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13
Q

what lab changes do you see that are specific for SLE flare?

A

complement levels drop and anti DS DNA levels rise

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14
Q

Antiphospholipid syndrome has as an elevated PT or PTT?

A

PTT

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15
Q

best initial test for antiphospholid syndrome?

A

mixing study- PTT will remain elevated in APL syndrome

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16
Q

most dangerous complication of sjogren

A

lymphoma

17
Q

best inital test for sjogren?

A

schirmer test

18
Q

best accurate test for sjogren?

A

lip or parotid gland biopsy

19
Q

antibodies in sjogren

A

ro and la

20
Q

antibodies in scleroderma

A

scl 70

21
Q

what should be tested for in polyarteritis nodosa

A

hep b and c

22
Q

unresolving pneumonia not better with antibiotics?

A

wegener

23
Q

antibodies associated with wegners

A

C ANCA

24
Q

term leukocytoclastic vasculitis on biopsy

A

henoch schonlein purpura

25
Q

complication of Henoch scholein purpura

A

intussusception

26
Q

what is cryoglobulins associated with?

A

hep C

27
Q

joint pain, glomerulonephritis, purpuric skin lesions neuropathy and history of Hep C

A

cryoglobulins

28
Q

asian or middle eastern person with painful oral and genital ulcers, painful nodules on skin, ocular lessions, arthritis

A

Behcets

29
Q

pencil in cup deformity

A

psoriatic arthritis

30
Q

treatment for psoriatic arthritis

A

1) NSAIDS
2) methotrexate
3) anti TNF

31
Q

Triad of joint pain, ocular findings, genital abnormalities secondary to IBD, STD GI infections

A

reiters syndrome

32
Q

most common organism that is involved in septic arthritis of recently placed artificial joints

A

Staphylococcus epidermidis

33
Q

what should you test for in recurrent gonorrheal infection

A

terminal complement deficiency

34
Q

radial tunnel syndrome

A

s/s similar to lateral epicondylitis,
tenderness over lie the extensor muscles
pain elicited by flexing the patients long finger while patient actively extends the finger and wrists.

35
Q

mood stabilizers

A

lithium
lamotrigine
valproate

36
Q

antipsychotis

A
aripiprazole
olanzapine
quietapine
risperidone
zipradisone