Rhematology Flashcards
Acute attack treatment for gout
1) NSAIDS- best initial therapy
2) corticosteroids
3) if can’t use NSAIDS or steroids then colchine
side effects of colchicine
diarrhea and bone marrow WBC supression ( neutropenia)
Drugs to avoid in gout
thiazides
niacin
aspirin
Best Bp med in gout
losartan
Pain worse when walking downhill, radiates into buttocks and thighs
lumbar spinal stenosis
anterior knee pain secondary to trauma worse just after starting walking after being seated for prolonged period. pain is particularly bad when going up and down stairs, normal x rays
pateollofemoral syndrome
Rhematoid arthritis
splenomegaly
neutropenia
Felty syndrome
Rheumatoid arthritis
pneumoconiosis
lung nodules
caplan syndrome
what are the adverse effects for methotrexate
liver toxicity
bone marrow suppression
pulmonary toxicity
you want to use TNF inhibitor such as infliximab, adalimumab, etanercept- what should you check before hand?
PPD- bc can cause reactivation of TB
Hydroxycholoroquine toxicity causes what?
retinal toxicity
presence of high spiking fevers in a young person with a salmon colored rash on chest and abdomen
juvenile rhematoid arthritis ( adult still disease)
what lab changes do you see that are specific for SLE flare?
complement levels drop and anti DS DNA levels rise
Antiphospholipid syndrome has as an elevated PT or PTT?
PTT
best initial test for antiphospholid syndrome?
mixing study- PTT will remain elevated in APL syndrome