Rhematology Flashcards
Acute attack treatment for gout
1) NSAIDS- best initial therapy
2) corticosteroids
3) if can’t use NSAIDS or steroids then colchine
side effects of colchicine
diarrhea and bone marrow WBC supression ( neutropenia)
Drugs to avoid in gout
thiazides
niacin
aspirin
Best Bp med in gout
losartan
Pain worse when walking downhill, radiates into buttocks and thighs
lumbar spinal stenosis
anterior knee pain secondary to trauma worse just after starting walking after being seated for prolonged period. pain is particularly bad when going up and down stairs, normal x rays
pateollofemoral syndrome
Rhematoid arthritis
splenomegaly
neutropenia
Felty syndrome
Rheumatoid arthritis
pneumoconiosis
lung nodules
caplan syndrome
what are the adverse effects for methotrexate
liver toxicity
bone marrow suppression
pulmonary toxicity
you want to use TNF inhibitor such as infliximab, adalimumab, etanercept- what should you check before hand?
PPD- bc can cause reactivation of TB
Hydroxycholoroquine toxicity causes what?
retinal toxicity
presence of high spiking fevers in a young person with a salmon colored rash on chest and abdomen
juvenile rhematoid arthritis ( adult still disease)
what lab changes do you see that are specific for SLE flare?
complement levels drop and anti DS DNA levels rise
Antiphospholipid syndrome has as an elevated PT or PTT?
PTT
best initial test for antiphospholid syndrome?
mixing study- PTT will remain elevated in APL syndrome
most dangerous complication of sjogren
lymphoma
best inital test for sjogren?
schirmer test
best accurate test for sjogren?
lip or parotid gland biopsy
antibodies in sjogren
ro and la
antibodies in scleroderma
scl 70
what should be tested for in polyarteritis nodosa
hep b and c
unresolving pneumonia not better with antibiotics?
wegener
antibodies associated with wegners
C ANCA
term leukocytoclastic vasculitis on biopsy
henoch schonlein purpura
complication of Henoch scholein purpura
intussusception
what is cryoglobulins associated with?
hep C
joint pain, glomerulonephritis, purpuric skin lesions neuropathy and history of Hep C
cryoglobulins
asian or middle eastern person with painful oral and genital ulcers, painful nodules on skin, ocular lessions, arthritis
Behcets
pencil in cup deformity
psoriatic arthritis
treatment for psoriatic arthritis
1) NSAIDS
2) methotrexate
3) anti TNF
Triad of joint pain, ocular findings, genital abnormalities secondary to IBD, STD GI infections
reiters syndrome
most common organism that is involved in septic arthritis of recently placed artificial joints
Staphylococcus epidermidis
what should you test for in recurrent gonorrheal infection
terminal complement deficiency
radial tunnel syndrome
s/s similar to lateral epicondylitis,
tenderness over lie the extensor muscles
pain elicited by flexing the patients long finger while patient actively extends the finger and wrists.
mood stabilizers
lithium
lamotrigine
valproate
antipsychotis
aripiprazole olanzapine quietapine risperidone zipradisone
