Neurology Flashcards

1
Q

male infant presents with muscular jerks and an uncle who has the same problem

A

Infantile spasms- west syndrome

  • generalized seizures @ 6 months of age
  • jerks head, trunk and extremities,
    • family history
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2
Q

Form of childhood onset seizures that are refractory to treatment

A

Lennox-Gastaut syndrome

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3
Q

Treatment for MS

A

Glatiramer and beta interferon are first lin e

Fingolimod, Natalizumab, mitoxantrone, azathioprine, cyclophosphamide

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4
Q

Treatment of ALS

A

Riluzole- slows down destruction of motor neurons, prevents glutamate buildup in neurons

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5
Q

Genetic disorder with loss of both motor and sensory innervation leading to distal weakness and sensory loss, wasting of legs, decreaseds DTRS, tremor

A

Charcot marie tooth disease

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6
Q

Biker, pressure on palms of hands, trauma to medial side of elbow- presents with wasting of hypothenar eminence, pain in fourth and fifth fingers

A

Ulnar

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7
Q

Pressure of inner, upper arm, falling asleep with arm over back of chair, using crutches and pressure in the axilla- presents with wrist drop

A

Radial

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8
Q

Obesity, pregnancy, sitting with legs crossed- presents with pain/numbness of outer aspect of one thigh

A

Lateral cutaneous nerve of thigh

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9
Q

Worsens with walking- presents with pain/numbness in ankle and sole of foot

A

Tarsal Tunnel

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10
Q

High boots, pressure on back of knee- presents with weak foot with decreased dorsiflexion and eversion

A

Peroneal

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11
Q

Typsists, carpenters, working with hands- presents with thenar wasting, pain/numbness in first 3 fingers

A

Median

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12
Q

treatment for GBS

A

plasmapheresis and IVIG

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13
Q

Parkinsonism + orthostatic hypotension, impotence, incontinence,

A

Shy drager syndrome

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14
Q

Pure motor stroke

A

internal capsule

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15
Q

pure sensory stroke

A

thalamus

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16
Q

What type of drug is levodopa/carbidopa?

A

Dopamine precursor

17
Q

What are side effects of levodopa/carbidopa?

A

Somnolence, confusion & hallucinations

dyskinesia

18
Q

What kind of drug is trihexyphenidyl?

A

Anticholinergic

19
Q

What kind of drugs are apomorphine, bromocriptine, pramipexole, and ropinirole

A

Dopamine agonist

20
Q

What kind of drug is entacapone and tolcapone

A

COMT inhibitor

21
Q

What kind of drug is selegiline?

A

MAO B inhibitor

22
Q

What side effects can be seen with trihexyphenidyl and benztropine

A
Dry mouth 
blurred vision 
constipation 
nausea
urinary retention
23
Q

What kind of side effects can be seen with Dopamine agonists

A

Somnolence, hypotension, and confusion

hallucinations

24
Q

What side effects can be seen with entacapone/ tolcapone

A

Dyskinesia, hallucinations, confusion, ausea, orthostatic hypotension

25
Q

what side effects are seen with selegiline?

A

Insomnia & confusion

26
Q

unilateral headache with a pulsatile quality, accompanied by vomiting and photophobia Treatment?

A

prochlorperazine +/- triptans and NSAIDS

27
Q

How can amitriptyline be used in migraines?

A

antidepressant that be used for migraine prophylactic

28
Q

Are DTR increased or decreased in diaetic polyneuropathy?

A

decreased

29
Q

GBS are DTR increased or decreased>

A

decreassed

30
Q

Within how many hours can you give TPA ?

A

3-4.5

31
Q

presentation of stroke symptoms was 6 hrs ago, what is appropriate therapy?

A

aspirin

32
Q

Difference between lewy body dementia and parkinson

A

see dementia early in lewey body compared to motor symptoms in parkinsons

33
Q

side effect of metoclopromide

A

dopamine receptor antagonist

  • increased peristalis, agitation, loose stools
  • extrapyramidal symptoms- tardive dyskinesia, dystonic reactions, parkinsonism
34
Q

Hemiplegic gait- spastic leg is extended and internally rotated. Walks by abducting and advancing spastic leg

A

corticospinal tract lesion

35
Q

slow onset of movement follower by increasingly rapid short shuffling steps

A

basal ganglia

36
Q

wide based erratic staggering gait

A

cerebellar