RHABDOMYOSARCOMA Flashcards
1
Q
What is RHABDOMYOSARCOMA
A
*It is the commonest soft tissue sarcoma in children under 15 years of age
2
Q
Variants of RHABDOMYOSARCOMA
A
*Alveolar,
*Embryonal
, *Pleomorphic
*Botryoid.
3
Q
Which variants have poor prognosis
A
*pleomorphic and alveolar types have poor prognosis
4
Q
Clinical Features
A
- painless subcutaneous mass,
- epistaxis & nasal congestion,
- swallowing problems, cranial nerve palsies
*symptoms depend on affected site
5
Q
Staging of tumor
A
STAGING
I- localised, no regional nodes involved
(wholly resectable)
II- resectable tumor with regional nodes
i n v o l v e d
III- gross residualdisease IV- distant metastases
6
Q
INVESTIGATIONS
A
*Tissue biopsy for histology,
*bone marrow biopsy,
*CT, CSF analysis (to rule out CNS involvement), RFT, LET
7
Q
TREATMENT
A
- Surgery,
*Radiation,
*Chemotherapy (done over a 28 day cycle using cyclophosphamide, actinomycin D & vincristine)
