Rh Labs

Question 1

Labs of SLE

Answer 1

-anemia / leukopenia (lymphopenia), thrombocytopenia
-ESR elevated during flare; CRP - nL
-positive Coombs
-Complement depressed during active disease
-

Question 2

antiphospholipid antibodies

Answer 2

(lupus anticoagulant / anticardiolipin)

-incr. risk of arterial/venous thromboses / libman-sacks endocarditis

Question 3

elevated anti-dsDNA

Answer 3

renal involvement

Question 4

anti-Sm

Answer 4

specific for lupus

-only present in 1/3 of pts

Question 5

anti-Ro / anti-La antibodies

Answer 5

-may cause congenital heart block in fetus

Question 6

diagnostic criteria for kawasaki disease

Answer 6

fever for 5+ days & 4 of:
1) acute - erythema of palms/soles + swelling hands/feet
chronic - periungal peeling toes/fingers
2) polymorphous exanthem
3) bilateral bulbar conjunctival injection
4) changes on lips/oral cavity (erythema, cracked lips, diffuse oral mucosa injection
5) cervical lymphadenopathy > 1.5 cm (unilateral)