Anemias Flashcards
1
Q
macrocytic megaloblastic anemias
A
vit b12
folate
orotic aciduria
2
Q
non-megaloblastic macrocytic anemias
A
aplastic anemia diamond-blackfan anemia bone marrow infiltration hypothyroidism fanconi anemia liver disease
3
Q
normocytic anemias
A
blood loss dec. RBC production incr. RBC destruction inherited hemolytic anemias acquired hemolytic anemias
4
Q
blood loss as cause of normocytic anemis
A
removal from the blood
acute blood loss
splenic sequestration
5
Q
dec. RBC prod. as cause of normocytic anemia
A
anemia of chronic disease
transient erythroblastopenia of childhood
chronic renal failure
malignant infiltration of the bone marrow
parvo b19 aplastic crisis
myelosuppressive agent drug toxicity
6
Q
inherited hemolytic anemias
A
abnl hemoglobin sickle cell thalessema RBC enzyme disorders G6PD def. pyruvate kinase deficiency RBC membrane disorders hereditary spherocytosis hereditary elliptocytosis
7
Q
acquired hemolytic anemias
A
antibody mediated anemias autoimmune hemolytic anemias isoimmune hemolytic anemias microangiopathic hemolytic anemias HUS DIC paroxysmal nocturnal hemoglobuinuria
8
Q
microcytic anemias
A
Fe deficiency severe lead poisoning thalessemia syndromes sideroblastic anemia ACD
9
Q
transient erythroblastopenia of childhood
A
normocytic anemia bone marrow suppression peak incidence 2 yo nL peripheral smear reticulocytopenia few erythroid precursors, normal myeloid/plt precursors
