Revision Flashcards
three pathogenic fungi
candida
aspergillus
cryptococcus
fungus associated with aids
pneumocytosis penumonia pcp
response to fungi
neutrophils macrophages monocytes, sensed by prrs innate. pamps=chtin mannans betaglucans
interferons
all cells respond to type I and make them
ifnalpha and beta
type two is gamma, produced by immune cells.
synthesis regulated by prrs and tlrs
ifns are secreted from infected cells, acts on itself and local cells to synthesise anti-viral genes.
ifn I moa
anti-viral genes transribed PKR shuts down translation Mx nullifies incoming genomes IFITM3 prevents entry of enveloped viruses tetherin prevents budding
how do viruses control ifns
hep c encodes proteases that destroy mavs
flu A binds to rig1 so pamp cant be detected
community acquired resp tract
legionella pneumophila
mycobacterium tuberculosis
community acquired std
chlamydia trachomatis
neisseria gonorrhoea
treponema pallidum-syphillis
community acquired food/water
bacillus anthracis vibrio cholera listeria monocytogenes shigella salmonella escherichia coli
community acquired vector borne
yersinia pestis - plague
community acquired vaccine preventable
corynebacterium diptheria neisseria meningitidis streptococcus pneumonia bordetella pertussis clostridium tetani
hospital acquired resistant +ve
pseudomonas aeruginosa - pneumonia, uti
ESBL, e coli klebsiella
Acinetobacter baumanii.
hospital acquired resistant -ve
MRSA
Enterococcus faecium
eskape
hospital acquired Enterococcus Staphylococcus aureus Clostridium difficile/Klebsiella pneumonia Acinetobacter baumanii Pseudomonas aeruginosa Escherichia coli
skin infections
staphylococcus aureus - +ve
treponema pallidum syphyllis
herpes simplex
varicella zoster virus chicken pox and shingles
trichophytum superficial fungal infections
scabies, mite infestation.
