revision 1 Flashcards

1
Q

key features of the endocrine system

A

diffusion
cell-cell
slow
long distance

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2
Q

key features of the nervous system

A

coarse
rapid
point-point
short

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3
Q

what are the three types of hormone

A

protein
cholesterol/steriod
amino acid

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4
Q

define hormone

A

chemical messenger made by specialised glands and transported to a target organ leading to a physiological response

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5
Q

define a gland

A

specalised cells for secretion

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6
Q

define an endocrine gland

A

ductless
hormones released into the blood
doesnt use any tubes

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7
Q

define an exocrine gland

A

has ducts

secretes fluids and enzymes

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8
Q

what is acromegaly?

A

hormonal disorder where the pituitary gland produces excess amounts of growth hormone.

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9
Q

whats the role of the adrenal cortext

A

outer portion of the adrenal gland and it produces steroid hormones, and mineralocorticoid hormones.

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10
Q

whats the role of the adrenal glands

A

regulate the stress response through synthesis of cortisol and adrenaline

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11
Q

what is adrenocorticotrophin? ATCH

A

hormone produced by the Ant pit that stimulates the adrenal gland

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12
Q

what is an androgen?

A

hormones that help develop sex organs and functions

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13
Q

whats the role of caalcitonin

A

protein hormone
secreted by cells in the thyroid gland
it inhibits bone degradation and stimulates the uptake of calcium and phosphate by bone

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14
Q

whats the role of cortisol

A

hormone produced by the adrenal glaand
involved in the stress response
increases blood pressure and blood sugar levels

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15
Q

cushings syndrome

A

hormonal disorder
caused by prolonged exposure of the tissues to high levels of cortisol
relatively rare

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16
Q

FSH

A

follicle stimulating hormone
controls the female menstrual cycle and production of eggs by the ovaries
high levels just before ovulation
in males in regulates sperm production

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17
Q

role of glucagon

A

hormone for carbohydrate metabolism
release when glucose levels in the blood are too low, hypoglycemia
causes the liver to convert stored glycogen into glucose

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18
Q

gonadatrophins

A

hormones that stimulate the growth and activity of the gonads

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19
Q

gonadatrophin releasing hormone GnRH

A

peptie hormone reponsible for the release of gonadatrophins from the ant pit
its made by the hypothalamus`

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20
Q

graves disease

A

most common form of hyperthyriodism

immune system attacks thyriod gland and causes it to over produce thryoxine

21
Q

role of the hypothalamus

A

area in the brain regulating vital autonomic centres

- produces hormones that control many body functions

22
Q

IGF-1

A

insulin like growth factor
polypeptide protein hormone similar in molecular structure to insulin
plays a role in childhood growth and anabolic effects in adults

23
Q

LH

A

Lutenising hormone

triggers ovulation in females

24
Q

oxytocin

A

hormone that acts as a neurotransmitter in the brain

facilitates childbirth/partuition and breastfeeding

25
parathryiod
make hormones used in calcium and phosphorus regulation
26
pineal gland
small endocrine gland at the centre of the brain and secretes melatonin used for sleeping and waking patterns
27
pituitary gland
located at the base of the skul | controls growth, BP breast milk production and metabolism
28
Polycystic ovary syndrome PCOS
endocrine disorder | cause by overproduction of male hormones in females
29
role of progesterone
female hormone that acts on the uterus to prepare it for reciving a fertilised egg when the levels fall it causes menstruation
30
prolactin
peptide hormone associated with lacatation | high levels during pregnancy stimulate milk production
31
steriods
set of molecules which includes some hormones that contain an arrangement of carbon rings include sex hormones, cortiocosteriods, anabolic steroids and cholesterol hormones
32
thymus gland
located in the chest behind the stermun | hormones produced bhere stimulate the production of immune cells and plays a role in T cell development
33
thyroid gland
inside the neck | regulates metabolism and the ability of the body to break down food and covert to energy
34
thyroid stimulatiing hormone
TSH, made by the hypothalamus and is transported by the AntPit to stimulate the hyriod to secrete its hormone thyroxine
35
vitamin D
fat soluble vitamin made by skin on exposure to UV rays from the sun active Vit D, D3, functions as a hormone sending messages to the intestine to increase absorption of calcium and phosporus
36
why do hormones take longer than neurones to induce their response
hormones act through second messengers or regulation of gene expression and these processes take longer for a reponse neuronal is direct stimulation so fast
37
where is oxytocin secreted from?
thypothalamus
38
where is aldosterone secreted from
adrenal gland
39
where is vasopresisn secreted from?
hypothalamus
40
where is calcitonin secreted from?
thyriod gland
41
describe paracrine signalling
hormones released into the blood affecting a distant site
42
describe autocrine signalling
hormones released into interstituim and act on cells nearby
43
describe the properties of peptide hormones
hydrophillic freely disolve and ciruclate in the blood short half life
44
how are peptide hormones synthesised
made as a pre-pro horomone then cleaved into prohormone then moved to golgi to be cleaved to active form and stored ready fror use
45
list the hormones the hypothalamus secretes
releasing hormones: GHRH, CRH, TRH, GnRH | stomatastain, dopamine, vaspressin, oxytocin
46
list the hormones the thyriod gland secretes
T3, T4 and calcitonin
47
list the hormones the adrenal gland secretes
cortisol, aldosterone, adrenal androgen, adrenaline and noradrenaline
48
list the hormones of the Ant Pit
``` corticotropin FSH LH prolactin thryoidotrophin growth hormone ```
49
list the hormones of the pos pit
oxytocin | vasopressin