Review Part 2 Flashcards
define Granulomatous Inflammation
a special form of chronic inflammation that is typically is not precede by an acute PMN-mediated inflammation
what causes Granulomatous Inflammation
it may be caused by antigens that evoke cell mediated hypersensitivity reaction or by antigens that persist at he site of inflammation
prototype Granulomatous Inflammation disease
TB (best example) and other fungal diseases
define serous inflammation
mildest form characterized by the erudition of fluid that is clear like serum, occurs at early stages
which inflammation is typical of viral infections
serous inflammation, vesicles caused by Herpesvirus
Best example of serous inflammation
Herpesvirus or second degree burns
Fibrinous Inflammation defintion
exudate that is rich in fibrin formed by long strands of polymerized fibrinogen
fibrin in places such as the heart can effect functioning
Example of fibrinous inflammation
bacterial infections such as Strept or pneumonia
Fibrinous Pericarditis
Define purulent inflammation
viscous yellow fluid composed of dead and dying PMN’s and necrotic tissue debris
what usually causes a purulent inflammation
pus forming bacteria such as staph or strept
what is an abscess
a localized collection of pus within an organ or tissue, consist of central portion of purulent material surrounded by a wall composed of a capsule of fibrotic granulation tissue
how do abscess heal?
they do not heal spontaneously and must be evacuated. drainage antibiotics
what happens with large abscess
they tend to rupture and form a sinus or fistula which are more common in chronic inflammation such as chromes disease
What is ulcerative inflammation
inflammation of body surfaces or the mucosa of hollow organs like the stomach or intestines
results in either an ulceration or loss of epithelial innings
Pseudomembranous Inflammation
A form of ulcerative inflammation that is combined with fibrinopurulent exudation forms pseudomembrane on the surface of the ulcers that can be scraped away
best example of ulcerative inflammation
gastric ulcer
best example of Pseudomembranous Inflammation
C difficile pseudomembranous colitis
Continuously Dividing Cells
Labile cells, divide throughout the entire lifespan
divide at regular rate and give rise to more differentiated cells. Think skin cells or mucosal ulcers
best example of continuously dividing cells
Stem cells, RBC division from bone marrow precursors
Quiescent cells
stable cells, can divide if necessary but do not divide regularly, once stable do not divide until needed again
Quiescent cells examples
parenchymal organs such as the liver or kidneys
Nondividing cells
permanent cells do not have the capacity to proliferate under any circumstances
Non dividing cell examples
neurons and myocardial cells, repairs are not functional
How does the body compensate for loss of myocardial cells
fibers scarring
How does the body compensate for loss of brain cells
Gliosis
define keloids
hypertrophic scars composed of predominantly type III collagen defective remodeling of scar tissue, result in immature scar
Signs of inflammation
calor, rubor, tumor, dolor, functio laesa
heat, redness, swelling, pain, loss of function
