REVIEW DRUGS 1 Flashcards

1
Q

What HTN drugs can be given in pregnancy (mentioned in class)?

A

methyldopa

hydralazine

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2
Q

If a pt comes in complaining of a severe dry cough, what drug are they probably on?

A

an ACE inhibitor (bc of increase in bradykinin levels)

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3
Q

If a pt has diabetic nephropathy, which drug would be a good choice to treat their hypertension?

A Omesartan
B Bisoprolol
C Amlodipine
D Moexipril

A

D. Moexipril

ACE inhibitors great for diabetic nephropathy as well

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4
Q

Which drug does NOT have a side effect listed as hyperkalemia?

A Captopril
B Telmisartan
C Bumetanide
D Aliskiren

A

C Bumetanide

Loop Diuretic– side effect would be a depletion of K

ACE inhibitors, ARB’s, Renin Inhibitors all indicate hyperkalemia as a side effect

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5
Q

If a pt has asthma, which drug should they for sure NOT take?

A Carvedilol
B Metoprolol
C Amlodipine
D Torsemide

A

A Carvedilol

A & B are both Beta Blockers… but A is a NON-selective beta blocker indicating probable bronoconstriction… so not good for pt’s with asthma

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6
Q

If a patient has acute angle closure glaucoma, what drug would be used to treat them? What dose?

A

Acetazolamid (CAI)- 2x250mg tablets

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7
Q

If a pt has heart failure, what class of drugs should NOT be used?

A

Ca2+ channel blockers!!

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8
Q

If a pt has cirrhosis of the liver, which drug would be contraindicated?

A Eplerenone
B Acetazolamid
C Methazolamid
D Perindopril
E all the above
F B and C
A

F- the CAI’s

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9
Q

Which drugs cause vasodilation due to the release of NO?

A

Nebivolol (Beta 1 selective inhibitor)
Hydralazine (Direct Vasodilator)
Nitroprusside (Parenteral agent)

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10
Q

Which drug can cause cyanide poisoning if given orally?

A

Nitroprusside

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11
Q

What two drugs can be given in a hypertensive emergency? BUT what if the pt has glaucoma?

A

Nitroprusside
Fenoldopam- DO NOT GIVE IF PT HAS GLAUCOMA
(parenteral agents)

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12
Q

Which class of drugs causes reflex tachycardia but no long term effects?

A

(-azosin) Alpha blocker…possibly need to gradually give drug

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13
Q

If a pt has tried several HTN drugs and none seem to be working, which drug should be proscribed?

A Hydralazine
B Verapamil
C Clonidine
D Terazosin

A

C. Clonidine

TRY Central Acting Alpha 2 Agonist

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14
Q

which drug can also help with a man wanting to grow some hair where he is balding…? LOL

A

Minoxidil

Called: Hypertrichosis

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15
Q

NSAIDS reduce the effectiveness of which drugs (due to P450 drug interactions):

A

Aliskiren (Reinin inhibitor)
Spironolactone (“K” sparring & aldosterone antag.)
Eplerenone (“K” sparring & aldosterone antag.)

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16
Q
If a patient has renal disease, which drug should be avoided?
A Amiloride 
B Amlodipine 
C Bumetanide
D Propanolol
A

A Amiloride (“K” sparring drugs! Think SEAT)

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17
Q

What class of drugs should ppl be tapered off of?

A

Beta Blockers

18
Q

If pt is being treated for hypertension and has had a previous heart attack or has agina pectoris or cluster headaches or another concomitant disease which class of drugs should be used?

A

Beta Blockers (-lol)

19
Q

What 5 things should be AVOIDED in HEART FAILURE?

A
NSAIDS
ALCOHOL
Ca2+ channel blockers
high dose beta blockers
some antiarrhythmic drugs
20
Q

If a pt is experiencing unexplained transient blurred vision and halos/altered color perception- what drug toxicity could be causing this?

21
Q

Which drugs should digoxin NOT be taken with?

A
amiodarone
erythromycin
quinidine
tetracycline
verapimil 

ALSO drugs that decrease K in the blood…so think diuretics:
Loop
Thiazide
corticosteroids

22
Q

Which of the following drugs can be used for HF at home?

A Digoxin
B Dobutamine
C Dopamine
D Milrinone

A

A- Digoxin

ALL other three are for HF with IV inpatient setting

23
Q

Name two first-line, single agent drugs that can be used to treat Heart Failure?

A

ANY ACE inhibitor: Fosinopril, Enalapril, etc…

24
Q

Which vasodilator do you NOT use with heart failure?

A

Ca2+ channel blocker!!!

25
What is isisorbide dinitrate?
Vasodilator
26
Beta blockers are used to treat only acute heart failure. True or False?
FALSE- only to treat CHRONIC HEART FAILURE
27
What is the go to drug for post heart attack- decrease incidence of sudden arrhythmic death?
Propanolol
28
What is the most widely used beta blocker for tx of cardiac arrhythmias?
metoprolol (also decrease risk of bronchospasm because beta one selective drug)
29
What is a short acting drug given by IV post-surgery or in emergency to tx arrythmia?
Esmolol
30
Drug of choice for atrial fibrillation?
Amiodarone (class III- potassium channel blocker)
31
What is the main ocular side-effect of Amiodarone?
Whorl Keratopathy
32
Which class III drugs pose the highest risk of proarrhythmia? 1. Amiodarone 2. Dofetilide 3. Dronedarone 4. Ibutilide 5. Sotalol
2. Dofetilide 4. Ibutilide Must CLOSELY MONITOR -tilide
33
If a pt complains of yellowing of vision and flashes, what drug is most likely causing this ocular issue?
Digoxin Ocular Toxicity (95% of cases)
34
Which anti-arrhythmic drug should not be taken with caffeine?
Adenosine
35
What three types of drugs are good for tx of angina?
nitrates (organic) Ca2+ channel blockers Beta Blockers
36
How should nitroglycerin be given?
significant FIRST-pass metabolism so....sublingual or as a patch (also...need a break in between so that tolerance does not occur)
37
What is the MOA of organic nitrates?
Enzyme activation of drug that causes a NO release
38
If angina is brought on by exercise and/or induces emotional stress....what should you take?
nitroglycerin
39
Don't use organic nitrates with what class of drugs?
Type 5 Phosphodiesterase inhibitors (aka the erectile dysfunction drugs...end in -afil)
40
Uh Oh...your pt comes in and tx of angina has failed when using Ca2+ channel blockers and nitroglycerin, what drug should you try for this CHRONIC angina?
Ranolazine (Na channel blocker)
41
What is the drug of choice for effort induced angina?
Beta Blockers (-lol)
42
What vasodilator can cause impaired color vision/blurry vision?
type 5 phosphodiesterase inhibitors (sildenafil (less likely), tadalafil, verdenafil)