Review Flashcards
1
Q
how long do red blood cells last
A
3- 4 months
2
Q
where are red blood cells broken down?
A
liver
spleen
3
Q
what is haem catabolised by?
A
haem oxygenase to iron and biliverdin
4
Q
what breaks down biliverdin
A
biliverdin reductase converting it to unconjugated bilirubin
5
Q
unconjugated bilirubin
A
not water-soluble so transported to the liver with albumin
6
Q
what is bilirubin conjugated with?
A
glucuronic acid
7
Q
uses of bile
A
- excretion of lipophilic toxins and substances too big for the kidney (bilirubin)
- cholesterol elimination
- immune function (IgA)
- emulsify dietary fat aiding absorption
8
Q
ALP and GGT raised
A
biliary damage
9
Q
ALP raised alone
A
bone not liver
10
Q
GGT raised with abnormal AST and ALT
A
alcohol
11
Q
AST raised but not ALT
A
less specific for liver
12
Q
other tests for chronic alcoholism
A
MCV
clotting
albumin
