Alcohol Dependence Flashcards
one unit of alcohol
10ml (8g)
define hazardous drinking
alcohol consumption that increases risk of harmful consequences
amount of alcohol defined as hazardous drinking
more than 14 units but less than 35 for women and 50 for men
define harmful drinking
alcohol consumption causing physical or mental damage
amount of alcohol defined as harmful drinking
more than 35 units for women and 50 units for men
define alcohol dependence
behaviour with a strong desire to drink alcohol and difficulties controlling use
DSM-IV
includes both alcohol abuse and dependence
DSM-5
combines abuse and dependence into a single disorder called alcohol use disorder (AUD)
what is the alcohol use disorders identification test (AUDIT)
10 question screening tool by WHO that measures physical and affective withdrawal, withdrawal relief drinking, consumption and rapidity of reinstatement
what is CIWA-AR
the clinical institute withdrawal assessment for alcohol (10 item scale to assess withdrawal)
complications of withdrawal
seizures, hallucinosis, delirium tremens and WK syndrome
chlordiazepoxide
treats withdrawal but high rate or relapse + kindling effect
acamprosate
action on GABA correcting electrolyte imbalance
naltrexone
opioid receptor antagonist reducing endorphins
disulfiram
deterrent due to bad reaction with alcohol BUT low compliance