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DIT Phase II Chapters > Review > Flashcards

Review Flashcards

1
Q

Anticholinergic SE (Dryness, confusion)

A

“PANDAH on a TRIcycle”

  • Promethazine
  • Atropine
  • Neuroleptics (low potency)
  • Digoxin
  • Amantadine
  • H1 blockers
  • TCAs
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2
Q

Coronary Vasospasm

A

“META takes Cocaine”

  • Methamphetamines
  • Ergotamines
  • Triptans
  • Amphetamines
  • Cocaine
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3
Q

Cutaneous Flushing

A

VAND

  • Vancomycin
  • Adenosine
  • Niacine
  • Dihydropyridine CCBs
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4
Q

Dilated Cardiomyopathy

A
  • Doxorubicin
  • Daunorubicin
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5
Q

Torsades de pointes

Rx?

A

13 CHaMP

  • Class IA sodium channel blockers
  • Class III potassium channel blockers
  • Chloroquine
  • Haloperidol
  • Macrolides
  • Protease Inhibitors

Rx for torsades: Push IV Magnesium

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6
Q

Agranulocytosis

A

3Cs, 2 thyroid drugs, Dap

  • Clozapine
  • Carbamaepine
  • Colchicine
  • PTU
  • Methimazole
  • Dapsone
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7
Q

Aplastic Anemia

A

CB MN for PTU

  • Chloramphenicol (gray baby)
  • Benzene
  • Methimazole
  • NSAIDs
  • PTU
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8
Q

Gray Baby Syndrome

A

Chloramphenicol

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9
Q

Hemolysis in G6PD-deficient patients

A

“eat Favas in PIINDANS country (red soiled area of Australia)”

  • Fava beans
  • Primaquine
  • Isoniazid, Ibuprofen
  • Naphthalene
  • Dapsone
  • high-dose Aspirin
  • Nitrofurantoin (UTIs)
  • Sulfonamides
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10
Q

Megaloblastic anemia

A

PMS no Zs

  • Phenytoin,
  • Methotrexate
  • Sulfa drugs
  • Zidovudine
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11
Q

Thrombocytopenia

A
  • Heparin (HIT)
  • H2 blockers (cimetidine)
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12
Q

Thrombosis

A

OCPs (especially if smoker >35 years old)

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13
Q

Pulmonary fibrosis

A
  • Bleomycin
  • Busulfan
  • Amiodarone (LFTs)
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14
Q

Acute cholestatic hepatitis

A

Erythromycin estolate (don’t give to patients with liver disease!)

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15
Q

Focal to massive hepatic necrosis

A

Kill your liver, HAVe A mushroom!

  • Halothane
  • Acetaminophen
  • Valproic acid
  • Amanita phalloides (mushroom toxin)
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16
Q

Hepatitis

A

Isoniazid (INH)

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17
Q

Pseudomembranous Colitis

A
  • Any antibiotic but notoriously:
  • Clindamycin
  • Ampicillin
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18
Q

Adrenocortical insufficiency

A

Withdrawal of Corticosteroids

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19
Q

Gynecomastia

A

*Booby’s got SMACKED! *

  • Spironolactone
  • Marijuana
  • chronic Alcohol use
  • Cimetidine
  • Ketoconazole
  • Estrogens
  • Digitalis
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20
Q

Hot Flashes

A
  • Tamoxifen
  • Clomiphene
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21
Q

Hypothyroidism

A
  • Amiodarone (TFTs),
  • Lithium
  • Sulfonamides
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22
Q

Hyperglycemia

A
  • Niacin
  • Tacrolimus
  • Protease inhibitors
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23
Q

Fat redistribution

A
  • Steroids
  • Protease inhibitors
  • HIV breaks down fat and causes sunken in facial features (temporal wasting),
  • Insulin injections
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24
Q

Gingival hyperplasia

A
  • Phenytoin
  • Verapamil
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25
Q

Gout

A

Diuresis:

Diuretics and Nic cycles up pyramid with gout

  • Furosemide
  • Thiazides
  • Niacin
  • Cyclosporin
  • Pyrazinamide
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26
Q

Myopathies

A

PSyCHING myopathies will elevate CPK

  • Penicillamine
  • Statins
  • Colchicine
  • Hydroxychloroquine
  • INF-alpha
  • Niacin
  • Glucocorticoids
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27
Q

$ Osteoporosis

A
  • Corticosteroids (if on for 3 months, get on bisphosphonate)
  • Heparin
28
Q

Photosensitivity

A
  • Sulfonamides
  • Amiodarone
  • Tetracycline
29
Q

Steven-Johnson Syndrome

A

Seizure drugs, Cillins and Sulfas:

  • Seizure meds: Ethosuximide, carbamazepine, lamotrigine, phenytoin, phenobarbital.
  • Penicillin
  • Sulfas
  • Allopurinol
30
Q

Drug-induced SLE

A

“SHIPP”

  • Sulfonamides
  • Hydralazine
  • INH
  • Procainamide
  • Phenytoin
31
Q

Tendon rupture/cartilage damage

A

Fluoroquinolones

32
Q

Nephrogenic DI

Rx for nephrogenic DI?

A
  • Lithium
  • Demeclocycline

Rx for DI - HCTZ, indomethacin, amiloride (add to lithium induced)

33
Q

Fanconi syndrome - proximal tubular defect

A
  • Expired tetracycline
  • Heavy metal exposure
  • Wilson disease
34
Q

Interstitial Nephritis

A
  • Methicillin
  • NSAIDS
  • Furosemide
35
Q

Hemorrhagic Cystitis

A
  • Cyclophosphamide
  • Ifosfamide (MESNA can prevent urotoxic metabolite from injuring the bladder)
36
Q

SIADH

A
  • Carbamazepine
  • Cyclophosphamide
37
Q

Cinchonism (Dizziness + headache + vision changes + tinnitus)

A
  • Quinidine (Class IA)
  • Quinine
38
Q

Reversible drug-induced parkinsons

A
  • Reserpine
  • Antipsychotics (haloperidol)
  • Metoclopramide
  • MTPT
39
Q

Seizures

A

“I IBM WEPT from a seizure”

  • Isoniazid, Imipenem/cilastatin
  • Buproprion
  • Metoclopramide
  • Withdrawal: Benzos or Alcohol
  • Enflurane
  • evening Primrose oil
  • Tramadol
40
Q

Tardive Dyskinesia

A

High Potency antipsychotics (Fluphenazine, Haloperidol)

41
Q

Disulfiram-like reaction

A

“Drink Corona at Midnight and Suffer Post Binge”

  • Disulfiram
  • Certain Cephalosporins,
  • Metronidazole
  • First-generation Sulfonylureas
  • Procarbazine (Anti-cancer alkylating agent)
42
Q

Nephrotoxic + Ototoxicity

A

Loop VAC

  • Loop diuretics
  • Vancomycin
  • Aminoglycosides
  • Cisplatin
43
Q

Acetaminophen

A

N-acetylcystine (relenishes glutathione)

Toxic dose - 12g in 24 hours

Max recommended dose - 4g in 24 hours

44
Q

Salicylates

A

Sodium Bicarbonate (alkalinize urine), dialysis

45
Q

Amphetamines

A

NH4Cl (acidify urine)

(ammonium chloride)

Amphetamines are basic

46
Q

Acetylcholinesterase inhibitors, organophosphates

A

Atropine, pralidoxime - regenerates acetylcholinesterase

47
Q

Antimuscarinic, anticholinergic agents

A

Physostigmine salicylate

48
Q

Beta blockers

A

Glucagon, Calcium, Atropine

49
Q

Digitalis

A

Stop dig; Atropine

KLAM - Potassium, Lidocaine, Anti-dig Fab fragments, magnesium

50
Q

Iron

A

Deferoxamine

51
Q

Lead

A

CaEDTA, dimercaprol, succimer, penicillamine

52
Q

Mercury, arsenic, gold

A

Dimercaprol (BAL), succimer

53
Q

Copper, arsenic, gold

A

Penicillamine

54
Q

Cyanide, from house fire or sodium nitroprusside OD

A

Nitrie, hydroxocobalamin, thiosulfate

55
Q

Methemoglobin

A

Methylene blue, vitamin C

56
Q

Carbon monoxide

A

100% O2, hyperbaric O2

57
Q

Methanol

A

Fomepizole > ethanol, dialysis

58
Q

Ethylene glycol (antifreeze)

A

Fomepizole > ethanol, dialysis

59
Q

Opioids

A

Naloxone/naltrexone

Often baby is OD due to mother receiving opioids for pain management in pregnancy

60
Q

Benzodiazepines

A

Flumazenil

61
Q

TCAs

A

Sodium bicarbonate (plasma alkalinization)

62
Q

Heparin

A

Protamine

63
Q

Warfarin

A

Vitamin K, fres frozn plasma

(Takes 3-5 days for clotting factos to come back online)

64
Q

PA, streptokinase, urokinase

A

Aminocaproic acid

65
Q

Theophylline

A

(Tacycardia)

Beta-blocker

DIT Phase II Chapters (10 decks)

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