Review Flashcards
Anticholinergic SE (Dryness, confusion)
“PANDAH on a TRIcycle”
- Promethazine
- Atropine
- Neuroleptics (low potency)
- Digoxin
- Amantadine
- H1 blockers
- TCAs
Coronary Vasospasm
“META takes Cocaine”
- Methamphetamines
- Ergotamines
- Triptans
- Amphetamines
- Cocaine
Cutaneous Flushing
VAND
- Vancomycin
- Adenosine
- Niacine
- Dihydropyridine CCBs
Dilated Cardiomyopathy
- Doxorubicin
- Daunorubicin
Torsades de pointes
Rx?
13 CHaMP
- Class IA sodium channel blockers
- Class III potassium channel blockers
- Chloroquine
- Haloperidol
- Macrolides
- Protease Inhibitors
Rx for torsades: Push IV Magnesium
Agranulocytosis
3Cs, 2 thyroid drugs, Dap
- Clozapine
- Carbamaepine
- Colchicine
- PTU
- Methimazole
- Dapsone
Aplastic Anemia
CB MN for PTU
- Chloramphenicol (gray baby)
- Benzene
- Methimazole
- NSAIDs
- PTU
Gray Baby Syndrome
Chloramphenicol
Hemolysis in G6PD-deficient patients
“eat Favas in PIINDANS country (red soiled area of Australia)”
- Fava beans
- Primaquine
- Isoniazid, Ibuprofen
- Naphthalene
- Dapsone
- high-dose Aspirin
- Nitrofurantoin (UTIs)
- Sulfonamides
Megaloblastic anemia
PMS no Zs
- Phenytoin,
- Methotrexate
- Sulfa drugs
- Zidovudine
Thrombocytopenia
- Heparin (HIT)
- H2 blockers (cimetidine)
Thrombosis
OCPs (especially if smoker >35 years old)
Pulmonary fibrosis
- Bleomycin
- Busulfan
- Amiodarone (LFTs)
Acute cholestatic hepatitis
Erythromycin estolate (don’t give to patients with liver disease!)
Focal to massive hepatic necrosis
Kill your liver, HAVe A mushroom!
- Halothane
- Acetaminophen
- Valproic acid
- Amanita phalloides (mushroom toxin)
Hepatitis
Isoniazid (INH)
Pseudomembranous Colitis
- Any antibiotic but notoriously:
- Clindamycin
- Ampicillin
Adrenocortical insufficiency
Withdrawal of Corticosteroids
Gynecomastia
*Booby’s got SMACKED! *
- Spironolactone
- Marijuana
- chronic Alcohol use
- Cimetidine
- Ketoconazole
- Estrogens
- Digitalis
Hot Flashes
- Tamoxifen
- Clomiphene
Hypothyroidism
- Amiodarone (TFTs),
- Lithium
- Sulfonamides
Hyperglycemia
- Niacin
- Tacrolimus
- Protease inhibitors
Fat redistribution
- Steroids
- Protease inhibitors
- HIV breaks down fat and causes sunken in facial features (temporal wasting),
- Insulin injections
Gingival hyperplasia
- Phenytoin
- Verapamil
Gout
Diuresis:
Diuretics and Nic cycles up pyramid with gout
- Furosemide
- Thiazides
- Niacin
- Cyclosporin
- Pyrazinamide
Myopathies
PSyCHING myopathies will elevate CPK
- Penicillamine
- Statins
- Colchicine
- Hydroxychloroquine
- INF-alpha
- Niacin
- Glucocorticoids
$ Osteoporosis
- Corticosteroids (if on for 3 months, get on bisphosphonate)
- Heparin
Photosensitivity
- Sulfonamides
- Amiodarone
- Tetracycline
Steven-Johnson Syndrome
Seizure drugs, Cillins and Sulfas:
- Seizure meds: Ethosuximide, carbamazepine, lamotrigine, phenytoin, phenobarbital.
- Penicillin
- Sulfas
- Allopurinol
Drug-induced SLE
“SHIPP”
- Sulfonamides
- Hydralazine
- INH
- Procainamide
- Phenytoin
Tendon rupture/cartilage damage
Fluoroquinolones
Nephrogenic DI
Rx for nephrogenic DI?
- Lithium
- Demeclocycline
Rx for DI - HCTZ, indomethacin, amiloride (add to lithium induced)
Fanconi syndrome - proximal tubular defect
- Expired tetracycline
- Heavy metal exposure
- Wilson disease
Interstitial Nephritis
- Methicillin
- NSAIDS
- Furosemide
Hemorrhagic Cystitis
- Cyclophosphamide
- Ifosfamide (MESNA can prevent urotoxic metabolite from injuring the bladder)
SIADH
- Carbamazepine
- Cyclophosphamide
Cinchonism (Dizziness + headache + vision changes + tinnitus)
- Quinidine (Class IA)
- Quinine
Reversible drug-induced parkinsons
- Reserpine
- Antipsychotics (haloperidol)
- Metoclopramide
- MTPT
Seizures
“I IBM WEPT from a seizure”
- Isoniazid, Imipenem/cilastatin
- Buproprion
- Metoclopramide
- Withdrawal: Benzos or Alcohol
- Enflurane
- evening Primrose oil
- Tramadol
Tardive Dyskinesia
High Potency antipsychotics (Fluphenazine, Haloperidol)
Disulfiram-like reaction
“Drink Corona at Midnight and Suffer Post Binge”
- Disulfiram
- Certain Cephalosporins,
- Metronidazole
- First-generation Sulfonylureas
- Procarbazine (Anti-cancer alkylating agent)
Nephrotoxic + Ototoxicity
Loop VAC
- Loop diuretics
- Vancomycin
- Aminoglycosides
- Cisplatin
Acetaminophen
N-acetylcystine (relenishes glutathione)
Toxic dose - 12g in 24 hours
Max recommended dose - 4g in 24 hours
Salicylates
Sodium Bicarbonate (alkalinize urine), dialysis
Amphetamines
NH4Cl (acidify urine)
(ammonium chloride)
Amphetamines are basic
Acetylcholinesterase inhibitors, organophosphates
Atropine, pralidoxime - regenerates acetylcholinesterase
Antimuscarinic, anticholinergic agents
Physostigmine salicylate
Beta blockers
Glucagon, Calcium, Atropine
Digitalis
Stop dig; Atropine
KLAM - Potassium, Lidocaine, Anti-dig Fab fragments, magnesium
Iron
Deferoxamine
Lead
CaEDTA, dimercaprol, succimer, penicillamine
Mercury, arsenic, gold
Dimercaprol (BAL), succimer
Copper, arsenic, gold
Penicillamine
Cyanide, from house fire or sodium nitroprusside OD
Nitrie, hydroxocobalamin, thiosulfate
Methemoglobin
Methylene blue, vitamin C
Carbon monoxide
100% O2, hyperbaric O2
Methanol
Fomepizole > ethanol, dialysis
Ethylene glycol (antifreeze)
Fomepizole > ethanol, dialysis
Opioids
Naloxone/naltrexone
Often baby is OD due to mother receiving opioids for pain management in pregnancy
Benzodiazepines
Flumazenil
TCAs
Sodium bicarbonate (plasma alkalinization)
Heparin
Protamine
Warfarin
Vitamin K, fres frozn plasma
(Takes 3-5 days for clotting factos to come back online)
PA, streptokinase, urokinase
Aminocaproic acid
Theophylline
(Tacycardia)
Beta-blocker
