Review #4 Flashcards

1
Q

Treatment for baby born to low viral mid mother with HIV

A

ZDV for 6 weeks

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2
Q

Timing of amniocentesis

A

15-20 wga (though can be done as soon as 11 wga)

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3
Q

Artery most often affected in puerperal hematomas of vulva / vagina

A

Pudendal

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4
Q

First line treatment for rapidly-expanding hematoma

A

Surgical evacuation

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5
Q

How to prevent Hep B vertical transmission if maternal viral load >200,000 between 28 and 32 wga

A

Administer lemivudine, telbivudine, or tenofovir at that time

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6
Q

High-risk inherited thrombophilias requiring anticoagulation during and after pregnancy

A

Factor V Leiden homozygote, prothrombin homozygote, compound Factor V and prothrombin heterozygote, antithrombin deficiency

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7
Q

Contraception with caveats for use in obesity

A

OCPs (increased VTE risk), patch (c/f decreased efficacy)

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8
Q

Warfarin lactation profile

A

Safe!

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9
Q

Mechanism of epinephrine

A

Beta-1 adrenergic receptor agonist

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10
Q

Timing for CVS

A

Between 10 and 13.6 wga

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11
Q

What / when to give calcium during transfusion?

A

1 g IV calcium chloride for every 4 units transfused

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12
Q

High-intensity statins

A

Atorvastatin or rosuvastatin

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13
Q

Recommended calcium intake for low BMD?

A

1000 - 1300 mg daily

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14
Q

Two most common histologies for vulvar cancer

A
  1. Squamous

2. Melanoma

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15
Q

When to discontinue mammograms

A

75 y/o

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16
Q

When to discontinue lung cancer screening

A

80 y/o

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17
Q

Pathology of pemphigoid gestationis

A

IgG antibodies mediate deposition of C3 complement at the basement membrane

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18
Q

Treatment for pemphigoid gestationis

A

Corticosteroids

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19
Q

Fetal effects of pemphigoid gestationis

A

Preterm delivery, SGA

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20
Q

Mechanism of PCN or cephalosporins

A

Inhibit peotidoglycan synthesis

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21
Q

Mechanism of tetracyclines and aminoglycosides

A

Bind 30S ribosomal subunit

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22
Q

Mechanism of macrolides

A

Bind 50S ribosomal subunit

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23
Q

How often should anti-epileptic drug levels be measured in pregnancy?

A

q4wks

24
Q

Most common microbe associated with breast abscess in setting of mastitis?

A

S. aureus

25
Q

Percent chance of concurrent endometrial adenocarcinoma with EIN

A

40%

26
Q

Pinard maneuver

A

Maneuver for delivery of legs from breech presentation, wherein the provider puts pressure behind knees to flex the leg

27
Q

Loveset maneuver

A

Maneuver for delivery of arms during breech delivery

28
Q

Frank breech

A

Pike position

29
Q

Treatment for superficial thrombophlebitis of the breast (Mondor disease)

A

NSAIDs, supportive care

10% associated with cancers, so perform age-appropriate screening

30
Q

Labs associated with subclinical hypothyroidism

A

High TSH, normal T4 / thyroxine

31
Q

Half life of T4 / thyroxine

A

1 week

32
Q

Extra calories to consume by trimester

A

1st - 220
2nd - 340
3rd - 450

33
Q

Pregnancy weight gain if BMI < 18.5

A

28 - 40 lbs

34
Q

Pregnancy weight gain if BMI 18.5 - 25

A

25 - 35 lbs

35
Q

Pregnancy weight gain if BMI 25 - 30

A

15 - 25 lbs

36
Q

Pregnancy weight gain if BMI > 30

A

11 - 20 lbs

37
Q

pH and base deficit associated with fetal morbidity

A

pH 7.12, base excess -12

38
Q

Surgical treatment for vulvodynia

A

Vestibulectomy

39
Q

VIN associated with squamous cell carcinoma

A

Differentiated, not HPV related (treat with WLE)

40
Q

What day of menstrual cycle should clomid be started?

A

2, 3, 4, or 5

41
Q

Genital ridge differentiates into…

A

Ovaries vs testes

42
Q

Gubernaculum turns into… (in female development)

A

Round and broad ligaments

43
Q

Origin of primordial germ cells

A

Yolk sac

44
Q

Development of the ovary

A

Primordial germ cells migrate to the genital ridge; coelomic epithelium cells surround oogonia to make granulosa; mesenchymal cells from the genital ridge form stroma

45
Q

Treatment for toxo in pregnancy

A

Spiramycin < 18 wga

Pyrimethamine-sulfadiazine > 18 wga

46
Q

E6

A

Produced by HPV, degrades p57

47
Q

E7

A

Produced by HPV, antiapoptotic effect on cells with abnormal p57

48
Q

Extremity more often affected by DVT in pregnancy

A

Left lower

49
Q

When to deliver accreta

A

34-36 wga

50
Q

Most thronbogenic thrombophilia

A

Antithrombin

51
Q

Which thrombophilia testing is unreliable in pregnancy?

A

Protein S deficiency

52
Q

Fetal apical displacement of the pulmonic valve most associated with which exposure?

A

Lithium (Ebstein anomaly)

53
Q

Most common genetic syndrome associated with tetralogy of Fallot

A

DiGeorge

54
Q

Forceps for head rotation

A

Kielland

55
Q

Forceps for molded head

A

Simpson