Review #4 Flashcards
Treatment for baby born to low viral mid mother with HIV
ZDV for 6 weeks
Timing of amniocentesis
15-20 wga (though can be done as soon as 11 wga)
Artery most often affected in puerperal hematomas of vulva / vagina
Pudendal
First line treatment for rapidly-expanding hematoma
Surgical evacuation
How to prevent Hep B vertical transmission if maternal viral load >200,000 between 28 and 32 wga
Administer lemivudine, telbivudine, or tenofovir at that time
High-risk inherited thrombophilias requiring anticoagulation during and after pregnancy
Factor V Leiden homozygote, prothrombin homozygote, compound Factor V and prothrombin heterozygote, antithrombin deficiency
Contraception with caveats for use in obesity
OCPs (increased VTE risk), patch (c/f decreased efficacy)
Warfarin lactation profile
Safe!
Mechanism of epinephrine
Beta-1 adrenergic receptor agonist
Timing for CVS
Between 10 and 13.6 wga
What / when to give calcium during transfusion?
1 g IV calcium chloride for every 4 units transfused
High-intensity statins
Atorvastatin or rosuvastatin
Recommended calcium intake for low BMD?
1000 - 1300 mg daily
Two most common histologies for vulvar cancer
- Squamous
2. Melanoma
When to discontinue mammograms
75 y/o
When to discontinue lung cancer screening
80 y/o
Pathology of pemphigoid gestationis
IgG antibodies mediate deposition of C3 complement at the basement membrane
Treatment for pemphigoid gestationis
Corticosteroids
Fetal effects of pemphigoid gestationis
Preterm delivery, SGA
Mechanism of PCN or cephalosporins
Inhibit peotidoglycan synthesis
Mechanism of tetracyclines and aminoglycosides
Bind 30S ribosomal subunit
Mechanism of macrolides
Bind 50S ribosomal subunit
How often should anti-epileptic drug levels be measured in pregnancy?
q4wks
Most common microbe associated with breast abscess in setting of mastitis?
S. aureus
Percent chance of concurrent endometrial adenocarcinoma with EIN
40%
Pinard maneuver
Maneuver for delivery of legs from breech presentation, wherein the provider puts pressure behind knees to flex the leg
Loveset maneuver
Maneuver for delivery of arms during breech delivery
Frank breech
Pike position
Treatment for superficial thrombophlebitis of the breast (Mondor disease)
NSAIDs, supportive care
10% associated with cancers, so perform age-appropriate screening
Labs associated with subclinical hypothyroidism
High TSH, normal T4 / thyroxine
Half life of T4 / thyroxine
1 week
Extra calories to consume by trimester
1st - 220
2nd - 340
3rd - 450
Pregnancy weight gain if BMI < 18.5
28 - 40 lbs
Pregnancy weight gain if BMI 18.5 - 25
25 - 35 lbs
Pregnancy weight gain if BMI 25 - 30
15 - 25 lbs
Pregnancy weight gain if BMI > 30
11 - 20 lbs
pH and base deficit associated with fetal morbidity
pH 7.12, base excess -12
Surgical treatment for vulvodynia
Vestibulectomy
VIN associated with squamous cell carcinoma
Differentiated, not HPV related (treat with WLE)
What day of menstrual cycle should clomid be started?
2, 3, 4, or 5
Genital ridge differentiates into…
Ovaries vs testes
Gubernaculum turns into… (in female development)
Round and broad ligaments
Origin of primordial germ cells
Yolk sac
Development of the ovary
Primordial germ cells migrate to the genital ridge; coelomic epithelium cells surround oogonia to make granulosa; mesenchymal cells from the genital ridge form stroma
Treatment for toxo in pregnancy
Spiramycin < 18 wga
Pyrimethamine-sulfadiazine > 18 wga
E6
Produced by HPV, degrades p57
E7
Produced by HPV, antiapoptotic effect on cells with abnormal p57
Extremity more often affected by DVT in pregnancy
Left lower
When to deliver accreta
34-36 wga
Most thronbogenic thrombophilia
Antithrombin
Which thrombophilia testing is unreliable in pregnancy?
Protein S deficiency
Fetal apical displacement of the pulmonic valve most associated with which exposure?
Lithium (Ebstein anomaly)
Most common genetic syndrome associated with tetralogy of Fallot
DiGeorge
Forceps for head rotation
Kielland
Forceps for molded head
Simpson