Review #3 Flashcards
BRCA1 lifetime breast cancer risk
55-70%
BRCA2 lifetime breast
45-70%
BRCA1 lifetime ovarian cancer risk
40%
BRCA2 lifetime ovarian cancer risk
15%
Other cancers associated with BRCA
Colon, prostate, pancreatic
Rates of pregnancy with perfect use of… OCPs, CuIUD, LNGIUD, Nexplanon
0.3, 0.6, 0.2, 0.05
Treatment for fibrocystic breast disease
NSAIDs, OCPs (danazol, tamoxifen in adults with pain not relieved by these treatments)
Systemic treatment for GSM
Ospemifene, a SERM approved for use in postmenopausal women with dyspareunia
Treatment for foul vaginal odor (with pessary, for example)
Oxyquinolone sulfate gel intravaginally 2-3 times per week
Muscle incised in midline episiotomy
Bulbospongiosus
Most common bacteria causing mastitis
S. aureus, coag neg staph, strep viridans
Embryo transfer most likely to be successful how many days after fertilization
5 (blastocyst)
Cyst of mongomery
Peri-areolar cyst, seen on ultrasound, most likely to resolve spontaneously
SERM causing endometrial polyps
Tamoxifen
Radiation dose generally considered safe for a fetus
50 mGy
History-indicated cerclage
One or more second trimester losses related to painless cervical dilation
Developmental cause of transverse vaginal septum
Failure of fusion of urogenital sinus and Mullerian ducts
Autoimmune disease associated with chlamydia infection
Reactive arthritis
Chlamydia treatment
Doxy 100 mg BID x7 days, or (if pregnant) azithromycin 1 g x1 dose
HIV screening interval for pregnant patient with HIV-positive partner (suppressed viral load)
qtrimester
Delivery timing for placenta previa
34.0 to 35.6 wga
Likelihood of accreta with previa by number of prior C/S
1% (none), 3% (one prior), 11%, 40%, 61%, 67%
What to do with measles exposure in pregnancy if known not to be immune
IVIG within 6 days of exposure
Tamiflu dosing: ppx vs tx
75 mg QD x10 d or 75 mg BID x5 d
Next step for “unsatisfactory cytology” pap
Repeat in 2-4 months (any age group)
Origins of uterovaginal nerve plexus
Inferior hypogastric plexus and sacral nerve roots
EPDS score c/f depression
> 12
Timing for rescue BMZ
At least 14 days
Pregnancy risks with anorexia
FGR, SGA, antepartum hemorrhage
Pregnancy risk with bulimia
SAB
Which ovarian vein more likely to be affected by thrombosis
Right
Max fluid deficit for electrolyte-poor fluid in hysteroscopy
1000 mL
Youngest age to initiate HPV-based testing for cervical cancer
35 y/o
Definition of recurrent pregnancy loss
2 or more clinically proven pregnancies
3 consecutive pregnancies (do not have to be clinically proven)
Initial work-up for RPL
Parental karyotype, uterine assessment, TSH, APLS labs
Johnson procedure
Standard attempt to reduce inverted uterus
Haultain procedure
Laparotomy with incision in posterior of uterus to reduce inversion
Huntington procedure
Laparotomy with serial clamping to reduce inversion
When to start ASA ppx
12 - 16 wga
Anti-epileptic associated with cleft palate
Topiramate
Anti-epileptic associated with major congenital malformations and cognitive / behavior teratogenesis
Valproate
Safest anti-epileptics in pregnancy
Lamotrigine, levetiracetam
Bacteria found in cultures from long-term IUD users
Actinomyces
Phenotype of newborn with congenital adrenal hypoplasia
Ambiguous genitalia (in XX individual)
What causes low aldosterone, low cortisol, and high testosterone at birth? (enzyme deficiency and disease name)
21-hydroxylase deficiency, leads to congenital adrenal hypoplasia
What defines FMR1 gene premutation?
CGG repeats 50-100
Disorders detected by NIPs
Trisomy 13, 18, 21, or sex chromosome disorders
Recommended pre-op testing for healthy patients over 65 y/o
CBC
Which progestin has anti-androgenic effects?
Drospirenone
Rotational forceps
Kielland
